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Latest David Sinclair Stories

Scientists Develop Chemical That May Stop Aging Process
2013-12-19 19:19:49

Brett Smith for redOrbit.com – Your Universe Online Through working with tiny cell structures called mitochondria, scientists may have unlocked one of the secrets of the aging process. According to a new study in the journal Cell, researchers found a sequence of molecular events that foster intracellular communication between the mitochondria and the nucleus. As this communication breaks down, the aging process speeds up. "The aging process we discovered is like a married couple...

2013-03-08 12:12:24

Findings identify universal mechanism for activating anti-aging pathway A new study demonstrates what researchers consider conclusive evidence that the red wine compound resveratrol directly activates a protein that promotes health and longevity in animal models. What's more, the researchers have uncovered the molecular mechanism for this interaction, and show that a class of more potent drugs currently in clinical trials act in a similar fashion. Pharmaceutical compounds similar to...

2012-05-01 21:19:57

New research reinforces the claim that resveratrol–a compound found in plants and food groups, notably red wine–prolongs lifespan and health-span by boosting the activity of mitochondria, the cell's energy supplier. "The results were surprisingly clear," said David Sinclair, a professor of genetics at Harvard Medical School and the study's senior author. "Without the mitochondria-boosting gene SIRT1, resveratrol does not work." Over the last decade, Sinclair and colleagues...

2011-11-01 21:14:11

When obese men take a relatively small dose of resveratrol in purified form every day for a month, their metabolisms change for the better. In fact, the effects appear to be as good for us as severe calorie restriction. Resveratrol is a natural compound best known as an ingredient in red wine. "We saw a lot of small effects, but consistently pointing in a good direction of improved metabolic health," said Patrick Schrauwen of Maastricht University in The Netherlands. The findings in the...

Scientists Question Resveratrol Longevity Products
2011-09-22 10:14:07

   New research suggests that anti-ageing face creams and supplements, that actively use a 'miracle ingredient' commonly found in red wine, are a complete waste of time and money, and do nothing to improve your odds of living a longer life. Resveratrol, which is credited with many of the health benefits of red wine, has become a staple for several beauty companies and is used in numerous products that can fetch prices of up to several hundreds of dollars for just a small...

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2011-04-20 07:50:00

According to new figures released this week, and based on data produced by the Office for National Statistics, more than 25 percent of British children 16 and under can expect to live to 100 years old. Just 30 years ago, more than a quarter of newborn boys were expected to die by their 65th birthday. Ministers said the rapid rise in longevity will have huge implications for public policy in a wide range of areas such as health and transportation, leaving taxpayers to pick up the tab on the...

2010-07-01 16:25:06

Better understanding of body's response to fasting may lead to therapies for metabolic disorders Massachusetts General Hospital (MGH) investigators have found that an enzyme with several important roles in energy metabolism also helps to turn off the body's generation of fats and cholesterol under conditions of fasting. The report in Genes & Development describes how SIRT1, one of a group of enzymes called sirtuins, suppresses the activity of a family of proteins called SREBPs, which...

2010-04-29 07:59:00

VIENNA, April 29, 2010 /PRNewswire/ -- Can Resveratrol, the so-called miracle molecule found in red wine, peanuts and an obnoxious plant called Chinese Giant Knotweed, actually improve your brain function? Scientists at Northumbria University in the UK have just published a double-blind, peer-reviewed study in the journal, American Journal of Clinical Nutrition, which concludes that a relatively modest dose of this compound in the form of one or two capsules may just do that. In...

2009-02-27 10:00:00

TORONTO, Feb. 27 /PRNewswire/ -- The following was written by W. Gifford-Jones M.D., a medical journalist. How do the French differ from North Americans? They eat fat-rich, calorie-packed baked goodies which are not heart healthy. Yet they're less likely to die from cardiovascular disease than North Americans. It's called "The French Paradox", believed to be linked to resveratrol, a substance found in red wine. Now, a study shows that a red wine pill provides more health benefits than...

2008-12-26 13:58:49

A Harvard professor and the California-based Shaklee Corp. differ on whether he approved the use of his name to promote a purportedly life-extending syrup. David Sinclair, a anti-aging researcher at Harvard Medical School, disputes Shaklee's contention that he approved use of his name in advertisements for the Vivix Cellular Anti-Aging Tonic, The Wall Street Journal reported Friday. Sinclair resigned from Shaklee's advisory board last week after the Journal questioned his seeming endorsement...


Word of the Day
endocarp
  • The hard inner (usually woody) layer of the pericarp of some fruits (as peaches or plums or cherries or olives) that contains the seed.
This word comes from the Greek 'endon,' in, within, plus the Greek 'karpos', fruit.
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