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Latest Deep brain stimulation Stories

2011-03-17 12:34:36

A first-of-its-kind study of gene therapy in the treatment of Parkinson's disease determined that half of all patients who received the treatment had "clinically meaningful improvements" of their symptoms within six months of surgery. "The study demonstrates that the promise of gene therapy for neurodegenerative disorders has become a reality," says study lead author and co-principal investigator Peter LeWitt, M.D., director of movement disorders at Henry Ford Health System. The new study is...

2011-03-17 12:32:49

Results from the first successful phase 2 clinical trial of gene therapy for Parkinson's or any neurologic disorder A gene therapy called NLX-P101 dramatically reduces movement impairment in Parkinson's patients, according to results of a Phase 2 study published today in the journal Lancet Neurology. The approach introduces a gene into the brain to normalize chemical signaling. The study is the first successful randomized, double-blind clinical trial of a gene therapy for Parkinson's or any...

2011-03-16 17:30:00

DETROIT, March 16, 2011 /PRNewswire/ -- A first-of-its-kind study of gene therapy in the treatment of Parkinson's disease determined that half of all patients who received the treatment had "clinically meaningful improvements" of their symptoms within six months of surgery. "The study demonstrates that the promise of gene therapy for neurodegenerative disorders has become a reality," says study lead author and co-principal investigator Peter LeWitt, M.D., director of movement disorders at...

2011-03-16 17:30:00

FORT LEE, N.J., March 16, 2011 /PRNewswire/ -- Neurologix, Inc. (OTC Bulletin Board: NRGX), announced today that the results of the Company's Phase 2 clinical trial for its novel, investigational gene therapy NLX-P101 for the treatment of Parkinson's disease (PD) were published in an online-first edition of The Lancet Neurology. The randomized, double-blind, sham surgery-controlled trial of 45 subjects with advanced PD met its primary outcome measurement for efficacy and demonstrated that...

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2011-03-10 13:59:11

Study uses NSF-supported technology to identify neuronal circuitry A new study sheds light--both literally and figuratively--on the intricate brain cell connections responsible for anxiety. Scientists at Stanford University recently used light to activate mouse neurons and precisely identify neural circuits that increase or decrease anxiety-related behaviors. Pinpointing the origin of anxiety brings psychiatric professionals closer to understanding anxiety disorders, the most common class of...

2011-03-09 13:57:05

Expectations for the improvement of a neurosurgical treatment, the deep brain stimulation (DBS) for movement disorders Movement disorders such as Parkinson's diseases and dystonia are caused by abnormal neural activity of the basal ganglia located deep in the brain. The basal ganglia are connected to the cerebral cortex in the brain surface through complex neural circuits. Their basic structure and connections, as well as the dysfunctions in movement disorders, have been examined extensively...

2011-03-09 13:01:34

Implanting electrodes into a pea-sized part of the brain can dramatically improve life for people with severe cervical dystonia "“ a rare but extremely debilitating condition that causes painful, twisting neck muscle spasms "“ according to the results of a pilot study led by Jill Ostrem, MD and Philip Starr, MD PhD at the University of California, San Francisco. Today, people with cervical dystonia can be treated with medications or injections of botulinum toxin (e.g.,...

2011-03-09 10:21:00

Noninvasive, deep brain therapy could benefit patients worldwide CHARLOTTESVILLE, Va., March 9, 2011 /PRNewswire-USNewswire/ -- A new chapter in medical history opened days ago when noninvasive MR-guided focused ultrasound was used to successfully treat a patient with essential tremor (ET), a progressive neurological disorder that affects millions of people worldwide and causes involuntary shaking of the hands, head, face, eyelids, voice or other muscles. The procedure has been...

2011-02-28 08:40:49

(Ivanhoe Newswire) -- New evidence shows when obsessive-compulsive disorder (OCD) becomes severe, deep brain stimulation (DBS) may help patients. However, one researcher says this method should be used with caution. Benjamin Greenberg, M.D., a psychiatrist from Brown University and Butler Hospital, discussed the results of the technique he's helped pioneer at the annual meeting of the American Association for the Advancement of Science. "These techniques are promising but must be used with an...

2011-02-23 22:17:39

The lateral habenula is hyperactive in rat models of human depression A team of neuroscientists at Cold Spring Harbor Laboratory (CSHL), Brookhaven National Laboratory (BNL) and UC San Diego (UCSD) has collected evidence suggesting that a previously overlooked portion of the brain could be a prime locus of human depression. In two rat models of human depression, the scientists have demonstrated that neurons in a tiny area in the central brain called the lateral habenula (LHb) are...