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Latest Dennis Selkoe Stories

2013-03-07 14:40:20

Research illuminates a molecular mechanism for why a stimulating environment may protect against Alzheimer's Disease "Use it or lose it." The saying could apply especially to the brain when it comes to protecting against Alzheimer's disease. Previous studies have shown that keeping the mind active, exercising and social interactions may help delay the onset of dementia in Alzheimer's disease. Now, a new study led by Dennis Selkoe, MD, co-director of the Center for Neurologic Diseases in...

2011-08-15 12:16:27

Shape of key protein surprises researchers A new study finds that a protein key to Parkinson's disease has likely been mischaracterized. The protein, alpha-synuclein, appears to have a radically different structure in healthy cells than previously thought, challenging existing disease paradigms and suggesting a new therapeutic approach. "Our data show that alpha-synuclein was essentially mistakenly characterized as a natively unfolded protein that lacked structure," said Dennis Selkoe, the...

2009-06-24 12:07:23

Scientists have uncovered a novel mechanism linking soluble amyloid ? protein with the synaptic injury and memory loss associated with Alzheimer's disease (AD). The research, published by Cell Press in the June 25 issue of the journal Neuron, provides critical new insight into disease pathogenesis and reveals signaling molecules that may serve as potential additional therapeutic targets for AD.Amyloid ? protein (A?) plays a major pathogenic role in AD, a devastating neurodegenerative disorder...


Word of the Day
snash
  • To talk saucily.
  • Insolent, opprobrious language; impertinent abuse.
This word is Scots in origin and probably imitative.