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Latest Dentate gyrus Stories

2013-07-23 12:29:37

Neural stem cells proliferate in the subventricular zone and hippocampal dentate gyrus of adult mammals. However, the number of endogenous neural stem cells is insufficient to prevent cerebral ischemia/reperfusion injuries such as vascular dementia, so it is important to stimulate endogenous neural stem cell proliferation and differentiation. The ginkgo biloba extract EGb761 effectively and safely treats memory loss and cognitive impairments in patients with senile dementia. Prof. Yuliang...

2013-06-05 12:31:39

CINCINNATI, June 5, 2013 /PRNewswire-USNewswire/ -- As pediatric specialists become increasingly aware that surgical anesthesia may have lasting effects on the developing brains of young children, new research suggests the threat may also apply to adult brains. (Logo: http://photos.prnewswire.com/prnh/20110406/MM79025LOGO) Researchers from Cincinnati Children's Hospital Medical Center report June 5 the Annals of Neurology that testing in laboratory mice shows anesthesia's neurotoxic...

Salk Researchers Study Neuroscience Behind Finding Lost Items
2013-03-21 18:20:17

Alan McStravick for redOrbit.com — Your Universe Online As if it wasn´t enough that Jonas Salk was responsible for the eradication of polio, now the institute named for him is tackling an even more universally deleterious condition: understanding the neural processes behind helping you to locate lost items. Though the results of the study have been adapted to the common human experience of finding one´s misplaced keys or automobile or cell phone, the research involved...

Specific Brain Region Plays Important Role In Reducing Anxiety
2013-03-07 09:13:26

April Flowers for redOrbit.com - Your Universe Online A research team led by the Columbia University Medical Center (CUMC) has found the first evidence that selective activation of the dentate gyrus, a portion of the hippocampus, can reduce anxiety without affecting learning. The findings suggest therapies targeting this brain region could treat certain anxiety disorders, such as panic disorder and post-traumatic stress syndrome (PTSD). These treatments, as described in the study, would...

2013-02-06 12:59:20

Researchers at the Institute for Comprehensive Medical Science, Fujita Health University and the National Institute for Physiological Sciences, Japan, along with colleagues from 9 other institutions, have identified an exceptional mouse model of schizophrenia. After screening over 160 mutant mouse strains with a systematic battery of behavioral tests, they identified a mutant mouse lacking the Schnurri-2 protein (Shn-2 KO) that exhibits behavioral deficits and other brain features consistent...

2012-09-19 16:45:40

Scientists have discovered the first direct evidence that a biological mechanism long suspected in epilepsy is capable of triggering the brain seizures — opening the door for studies to seek improved treatments or even preventative therapies. Researchers at Cincinnati Children's Hospital Medical Center report Sept. 19 in Neuron that molecular disruptions in small neurons called granule cells — located in the dentate gyrus region of the brain — caused brain seizures in...

2012-09-19 06:27:47

CINCINNATI, Sept. 19, 2012 /PRNewswire-USNewswire/ -- Scientists have discovered the first direct evidence that a biological mechanism long suspected in epilepsy is capable of triggering brain seizures - opening the door for studies to seek improved treatments or even preventative therapies. (Logo: http://photos.prnewswire.com/prnh/20110406/MM79025LOGO) Researchers at Cincinnati Children's Hospital Medical Center report Sept. 19 in Neuron that molecular disruptions in small neurons called...

2011-08-31 23:17:18

Memo to mature, health-minded vampires: You might want to consider limiting your treats to victims under age 30. In a study to be published Sept. 1 in Nature, Stanford University School of Medicine scientists have found substances in the blood of old mice that makes young brains act older. These substances, whose levels rise with increasing age, appear to inhibit the brain's ability to produce new nerve cells critical to memory and learning. The findings raise the question of whether it...

2011-06-23 15:40:09

From the Petri dish into a living organism, for the first time U-M scientists observe key aspects of how the brain shapes itself Scientists at the University of Michigan Health System have for the first time demonstrated how memory circuits in the brain refine themselves in a living organism through two distinct types of competition between cells. Their results, published today in Neuron, mark a step forward in the search for the causes of neurological disorders associated with abnormal brain...

2010-10-04 22:58:35

A researcher from the Faculty of Medicine & Dentistry at the University of Alberta has discovered a mechanism underlying some forms of obesity and addictions which could lead to a treatment for both diseases. When a hungry animal finds food in the wild, it is a rewarding stimulus for the animal and is recognized by the brain by the release of the chemical messenger dopamine. Because narcotics such as cocaine, heroin and amphetamines, and even tasty and highly-caloric foods also cause the...