Latest Diglyceride acyltransferase Stories

2012-11-01 23:12:39

Congenital diarrheal disorders (CDD) are a group of rare intestinal diseases that are caused by genetic mutations. In a study published in the Journal of Clinical Investigation, Robert Farese and colleagues at the University of California, San Francisco, identified a family with two of three children affected by CDD. The affected children both carried a rare mutation in the DGAT1 gene. DGAT1 mediates the formation of triglycerides and is being assessed as a therapeutic target in the treatment...

2009-02-18 09:13:09

Scientists have discovered that an enzyme associated with the synthesis of fat in the body also promotes healthy skin and hair. The enzyme is called acyl COA: diacylglycerol acyltransferase or DGAT1. Researchers found mice that lack DGAT1 are lean, resistant to diet-induced obesity, are more sensitive to insulin and leptin and have abnormalities in mammary gland development and skin. When researchers deleted the enzyme in mice, they found that a lack of DGAT1 caused levels of retinoic acid...

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  • A beast of burden; also, a beast in general.
'Jument' ultimately comes from the Latin 'jugum,' yoke.