Latest DNA-binding protein Stories
In the cell nucleus, DNA wraps around what are called histone proteins, forming regularly spaced spherical bodies called nucleosomes. Thus, large portions of the genetic material are inaccessible to the gene reading machinery. Scientists at the German Cancer Research Center have now simulated at high time resolution how short DNA segments repeatedly detach spontaneously from the nucleosome. The group has been the first to demonstrate that the spool-shaped histone proteins have an active role...
A novel technique has been developed and demonstrated at Penn State University to map the proteins that read and regulate chromosomes -- the string-like structures inside cells that carry genes. The specific order in which these proteins attach DNA-containing nucleosomes along the chromosome determines whether a brain cell, a liver cell, or a cancer cell is formed. Until now, it has been exceedingly difficult to determine exactly where such proteins bind to the chromosome, and therefore how...
- Like a worm in form or movement; vermiform; tortuous or sinuous; also, writhing or wriggling.
- Like the track or trace of a worm; appearing as if worm-eaten; vermiculate.
- Marked with fine, close-set, wavy or tortuous lines of color; vermiculated.
- A form of rusticated masonry which is so wrought as to appear thickly indented with worm-tracks.