Latest DNA Chip Stories
By Liu, Jun Jin, Taocong; Chang, Syweren; Ritchie, Helena H; Et al Abstract We have recently reported the induction of dental pulp stem cells (DPSCs) into dentin-secreting odontoblast-like cells after stimulation by isolated dentin matrix components, thus mimicking the nature of tissue regeneration seen after tooth disease and injury. After confluency, the cells were further cultured for 21 d in the 10% fetal bovine serum (FBS) Dulbecco's modified Eagle's medium (DMEM) (control), and in this...
By Raspollini, Maria Rosaria; Oliva, Esther; Roberts, Drucilla J Abstract The purpose of this article is to review the histopathologic findings in the placenta of women with a known thrombophilic mutation. The findings range from normal to severe pathologic features including decidual vasculopathy, placental infarctions, syncytial knotting, maternal floor infarction, fetal thrombotic vasculopathy, vasculitis, and chronic villitis. They are, however, not pathognomonic of thrombophilic...
TOKYO (Reuters) - Toshiba Corp. said on Friday it had licensed patents on DNA chips and DNA detection and analysis to California-based Antara BioSciences Inc. Antara, established in 2005 by unlisted Tokyo-based genome research start-up Eurus Genomics, plans to use the patents to develop for sale in the United States DNA chips and systems used in in-vitro diagnosis of disease in humans, Toshiba said in a statement. A Toshiba spokeswoman declined to disclose the financial details of the...
BOSTONÂ - A newly identified gene expression profile could help predict how patients with advanced ovarian cancer will respond to chemotherapy treatment. Described in a study in the November 1, 2005 issue of The Journal of Clinical Oncology (JCO), the new findings further establish an important role for microarray gene profiling as a predictor of clinical outcome in ovarian cancer, and could eventually provide clinicians with insights into the mechanisms of drug resistance. "In many...
CHAMPAIGN, Ill. -- Using newly available biological technology, researchers have developed the first molecular portrait of multiple gene activity in diseased heart tissue taken from dogs near death from a devastating disease. The discovery sheds new light on the heart's response to dilated cardiomyopathy (DCM), a disease of large-breed dogs. New microscopic technology allows researchers to place tens of thousands of genes on 1.5-inch-square slides known as a microarray. In this case,...
CAMBRIDGE, Mass. - Just as the printing press revolutionized the creation of reading matter, a "nano-printing" technique developed at MIT could enable the mass production of nano-devices currently built one at a time. The most immediate candidate for this innovation is the DNA microarray, a nano-device used to diagnose and understand genetic illnesses such as Alzheimer's, viral illnesses such as AIDS, and certain types of cancer. The ability to mass produce these complex devices...
