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Latest DNA Chip Stories

2008-11-06 11:17:54

Signature Genomic Laboratories, a provider of microarray-based cytogenetic diagnostics, has launched a new enhanced microarray for the prenatal detection of chromosome abnormalities that result in missing or extra pieces of DNA. The first tier of Signature's prenatal service, the enhanced PrenatalChip targets over 100 discrete chromosomal regions, the gain or loss of which results in a genetic disorder, while minimizing coverage of regions of unknown clinical significance. Signature's...

2008-11-05 12:00:30

Signature Genomic Laboratories announced the release of an enhanced microarray for the prenatal detection of chromosome abnormalities that result in missing or extra pieces of DNA. The first tier of Signature's Prenatal Service, the enhanced PrenatalChip(R) targets over 100 discrete chromosomal regions, the gain or loss of which results in a genetic disorder, while minimizing coverage of regions of unknown clinical significance. Signature's whole-genome microarray, the SignatureChipWG,...

2008-10-31 09:00:28

SUNNYVALE, Calif., Oct. 31 /PRNewswire/ -- Pathwork Diagnostics, a molecular diagnostics company focused on oncology, will present three studies involving the gene expression based Pathwork(R) Tissue of Origin Test at the Association for Molecular Pathology (AMP) Annual Meeting. In a poster entitled, "Gene Expression Microarray-Based Diagnostic Test May Identify Primary Tumor Site in Patients with Carcinoma of Unknown Primary (CUP)," Fabiola Medeiros, MD, Assistant Professor of Laboratory...

2008-10-30 09:00:40

Finnish biotechnology company Mobidiag launches its first CE-marked product for In Vitro Diagnostics (IVD) of sepsis. The microarray-based Prove-it(TM) Sepsis is invincible in both the coverage and the rate of detecting dangerous bacteria including the superbug MRSA from positive blood culture samples in a single test. The test enables simultaneous identification of 50 species in less than three hours. Based on the excellent performance of 3300 patient samples in the University College London...

2008-08-27 03:00:26

By Zhao, Qiao Brkljacic, Jelena; Meier, Iris Ran GTPase plays essential roles in multiple cellular processes, including nucleocytoplasmic transport, spindle formation, and postmitotic nuclear envelope (NE) reassembly. The cytoplasmic Ran GTPase activating protein RanGAP is critical to establish a functional RanGTP/RanGDP gradient across the NE and is associated with the outer surface of the NE in metazoan and higher plant cells. Arabidopsis thaliana RanGAP association with the root tip NE...

2008-08-26 15:01:06

Signature Genomic Laboratories, a company that specializes in microarray-based diagnostic testing of genetic disease in individuals with mental retardation and birth defects, announced it has waived the 25% deposit previously required of patients for insurance billing. Rather than pay a deposit prior to the initiation of testing, patients with private insurance can request an insurance benefits investigation prior to or concurrent with sample processing through Signature's recently...

2008-08-18 12:00:55

Researchers at Signature Genomic Laboratories recently published the first large-scale prospective study comparing the detection rate of chromosomal abnormalities--missing or extra pieces of DNA--by microarray analysis in prenatal cases to that of neonatal cases referred with a variety of clinical findings, including congenital anomalies. In the study, the findings of which will appear in the September issue of the journal Prenatal Diagnosis and were electronically published July 22,...

2008-07-31 09:01:26

Affymetrix Inc. (Nasdaq:AFFX) announced today that the U.S. Food and Drug Administration (FDA) has granted regulatory clearance to its GCS3000Dx (GCSDx) platform for in vitro gene expression diagnostic testing. The microarray system was granted clearance along with the Pathwork(R) Tissue of Origin (TOO) Test from Pathwork Diagnostics Inc. This test analyzes a tumor's gene expression profile to aid in diagnosing the source of hard-to-identify tumors and is the first of its kind to receive FDA...

2008-07-17 12:01:18

Expression Analysis, Inc., the industry's leading provider of genomic services for clinical trails and research, announced today that it has entered into a scientific collaboration with The Immunological Genome Project to provide microarray expression profiling services for this NIH funded project. The project will generate, under rigorous standardized conditions, a complete microarray dissection of gene expression in the immune system of the mouse. The focus is on primary cells ex vivo....

2008-06-24 03:02:21

By Ferreira, Fernando J Guo, Cathy; Coleman, John R Carbonic anhydrase (CA; EC 4.2.1.1) catalyzes the interconversion of CO^sub 2^ and HCO^sub 3^^sup -^ and is a major protein constituent of the C^sub 3^ higher plant chloroplast where it is presumed to play a role in photosynthetic carbon assimilation. In this study, we have used both RNA antisense and gene knockout lines to specifically reduce the activity of the chloroplast betaCA1 polypeptide (At3g01500) in the model plant Arabidopsis...