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Latest DNA Chip Stories

2008-06-24 03:00:08

By Rudd, Jason J Keon, John; Hammond-Kosack, Kim E Many race- or isolate-specific disease resistance responses of plants toward pathogens (incompatible interactions) invoke hypersensitive response (HR)-like programmed cell death (PCD) and the coordinated activation of mitogen-activated protein kinases homologous with Arabidopsis (Arabidopsis thaliana) AtMPK6 and AtMPK3 (or tobacco [Nicotiana tabacum] SIPK and WIPK), respectively. Resistance of wheat (Triticum aestivum) leaves to the...

2008-04-30 03:00:11

By Pasinetti, Giulio M Hiller-Sturmhofel, Susanne Systems biology approaches may be useful for studying the mechanisms underlying alcohol's harmful effects on the brain. Such approaches already are used in the study of Alzheimer's disease (AD), a progressive neurodegenerative disorder that, with the overall increase in life expectancy, will affect an increasing proportion of the population and become an increasingly serious public health concern. Systems biology approaches such as...

2008-04-22 09:01:15

Affymetrix Inc. (Nasdaq:AFFX) today announced that Pathwork Diagnostics Inc. will begin offering a molecular diagnostic test based on the Affymetrix microarray platform. The Pathwork Tissue of Origin Test is one of the first microarray-based diagnostic tests for cancer in the United States. The test is being made available through the recently CLIA-certified Pathwork® Diagnostics Laboratory. There are an estimated 200,000 patients with uncertain primary tumors,...

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2008-03-31 11:10:00

Some of the worst threats to farm workers and farm animals such as bird flu, foot-and-mouth disease and other emerging viruses could soon be quickly identified by using a simple screening chip developed by scientists from the Institute for Animal Health, scientists will hear today (Monday 31 March 2008) at the Society for General Microbiology's 162nd meeting being held this week at the Edinburgh International Conference Centre."The last major SARS outbreak "“ severe acute respiratory...

2007-07-03 09:17:00

By Liu, Jun Jin, Taocong; Chang, Syweren; Ritchie, Helena H; Et al Abstract We have recently reported the induction of dental pulp stem cells (DPSCs) into dentin-secreting odontoblast-like cells after stimulation by isolated dentin matrix components, thus mimicking the nature of tissue regeneration seen after tooth disease and injury. After confluency, the cells were further cultured for 21 d in the 10% fetal bovine serum (FBS) Dulbecco's modified Eagle's medium (DMEM) (control), and in...

2007-03-18 03:00:12

By Raspollini, Maria Rosaria; Oliva, Esther; Roberts, Drucilla J Abstract The purpose of this article is to review the histopathologic findings in the placenta of women with a known thrombophilic mutation. The findings range from normal to severe pathologic features including decidual vasculopathy, placental infarctions, syncytial knotting, maternal floor infarction, fetal thrombotic vasculopathy, vasculitis, and chronic villitis. They are, however, not pathognomonic of thrombophilic...

2006-03-10 09:34:35

TOKYO (Reuters) - Toshiba Corp. said on Friday it had licensed patents on DNA chips and DNA detection and analysis to California-based Antara BioSciences Inc. Antara, established in 2005 by unlisted Tokyo-based genome research start-up Eurus Genomics, plans to use the patents to develop for sale in the United States DNA chips and systems used in in-vitro diagnosis of disease in humans, Toshiba said in a statement. A Toshiba spokeswoman declined to disclose the financial details of...

2005-11-03 15:30:26

BOSTON - A newly identified gene expression profile could help predict how patients with advanced ovarian cancer will respond to chemotherapy treatment. Described in a study in the November 1, 2005 issue of The Journal of Clinical Oncology (JCO), the new findings further establish an important role for microarray gene profiling as a predictor of clinical outcome in ovarian cancer, and could eventually provide clinicians with insights into the mechanisms of drug resistance. "In many...

2005-07-06 16:33:03

CHAMPAIGN, Ill. -- Using newly available biological technology, researchers have developed the first molecular portrait of multiple gene activity in diseased heart tissue taken from dogs near death from a devastating disease. The discovery sheds new light on the heart's response to dilated cardiomyopathy (DCM), a disease of large-breed dogs. New microscopic technology allows researchers to place tens of thousands of genes on 1.5-inch-square slides known as a microarray. In this case,...

2005-06-07 17:32:52

CAMBRIDGE, Mass. - Just as the printing press revolutionized the creation of reading matter, a "nano-printing" technique developed at MIT could enable the mass production of nano-devices currently built one at a time. The most immediate candidate for this innovation is the DNA microarray, a nano-device used to diagnose and understand genetic illnesses such as Alzheimer's, viral illnesses such as AIDS, and certain types of cancer. The ability to mass produce these complex devices would make...