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Latest DNA damage theory of aging Stories

Our Aging Process Is Hastened Due To Maternal Genetics
2013-08-22 08:28:26

April Flowers for redOrbit.com - Your Universe Online There are many reasons our bodies age. The process is determined by an accumulation of various kinds of cell damage that impair the function of bodily organs. A new study from the Karolinska Institutet and the Max Planck Institute for Biology of Aging shows the damage occurring in the cell’s power plant – the mitochondrion – is of particular importance in the aging process and is determined by the genes we inherit from our...

2012-06-16 01:07:59

Previously unknown repair byproduct could be ℠master regulator´ of many basic cell processes University of Texas Medical Branch at Galveston researchers have found a surprising connection between a key DNA-repair process and a cellular signaling network linked to aging, heart disease, cancer and other chronic conditions. The discovery promises to open up an important new area of research – one that could ultimately yield novel treatments for a wide variety of diseases....

2012-06-11 05:25:53

(Ivanhoe Newswire) --A game-changing find challenges previously held beliefs about the role of mutations in cancer development. Researchers at the Fred Hutchinson Cancer Research Center in Seattle say their findings show that the number of new mutations is significantly lower in cancers than in normal cells. "This is completely opposite of what we see in nuclear DNA, which has an increased overall mutation burden in cancer," cancer geneticist Jason Bielas, Ph.D., an assistant member of the...

2012-02-03 06:23:43

(Ivanhoe Newswire) James D. Watson, Frances Crick, and Maurice Wilkins were awarded the Nobel Prize in Physiology or Medicine in 1962 for their discovery of the structure of DNA. Using x-ray diffraction data, they found that the structure of the DNA molecule was shaped like a double helix or spiral staircase. Today, researchers continue their efforts in understanding DNA. Researchers at Uppsala University collaborated with others, from Hudson Alpha Institute for Biotechnology, as well as...

2011-06-16 21:29:36

Findings could lead to treatments to prevent premature aging and cancer Cells in the human body are constantly being exposed to stress from environmental chemicals or errors in routine cellular processes. While stress can cause damage, it can also provide the stimulus for undoing the damage. New research by a team of scientists at the University of Rochester has unveiled an important new mechanism that allows cells to recognize when they are under stress and prime the DNA repair machinery to...

2009-09-07 14:31:17

A study that tracked genetic mutations through the human equivalent of about 5,000 years has demonstrated for the first time that oxidative DNA damage is a primary cause of the process of mutation - the fuel for evolution but also a leading cause of aging, cancer and other diseases. The research, just published in Proceedings of the National Academy of Sciences, also indicated that natural selection is affecting the parts of the genome that don't contain genes "“ supposedly "junk" DNA...

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2009-07-01 10:55:00

Deleting two genes in mice responsible for repairing DNA strands damaged by oxidation leads to several types of tumors, providing additional evidence that such stress contributes to the development of cancer. That's the conclusion of a recent study* in DNA Repair by researchers at the National Institute of Standards and Technology (NIST), Oregon Health and Science University (OHSU) and the New York University School of Medicine (NYUSM).Although all cells need oxygen to survive, the element...

2009-01-15 10:17:09

Scientists at St. Jude Children's Research Hospital have teased apart the biological details distinguishing two related neurological diseases"”ataxia telangiectasia-like disease (ATLD) and Nijmegen breakage syndrome (NBS). Both disorders arise from defects in a central component of the cell's machinery that repairs damaged DNA, but each disease presents with distinct pathologies. Defects in DNA repair dramatically increase the risk of cancer, which is found in NBS. However, NBS is also...

2009-01-14 16:28:00

St. Jude scientists' findings in ataxia telangiectasia-like disease and Nijmegen breakage syndrome offer insight into the links between brain disease and cancer vulnerability in people carrying the diseases MEMPHIS, Tenn., Jan. 14 /PRNewswire-USNewswire/ -- Scientists at St. Jude Children's Research Hospital have teased apart the biological details distinguishing two related neurological diseases--ataxia telangiectasia-like disease (ATLD) and Nijmegen breakage syndrome (NBS). Both...

2005-09-16 13:50:00

HOUSTON --  When Dr. Susan Rosenberg, professor of molecular and human genetics at Baylor College of Medicine, first published her finding that the mutation rate increased in bacteria stressed by starvation, sometimes resulting in a rare change that benefited the bacteria, it was controversial. In a report in the current issue of the journal Molecular Cell, she and her colleagues describe not only how it happens but also show that this only occurs at a special time and place in the...


Word of the Day
penuche
  • A fudgelike confection of brown sugar, cream or milk, and chopped nuts.
'Penuche' is a variant of 'panocha,' a coarse grade of sugar made in Mexico. 'Panocha' probably comes from the Spanish 'panoja, panocha,' ear of grain.
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