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Latest DNA demethylation Stories

2011-10-03 15:30:12

Finding has implications for treatment of wide range of diseases Johns Hopkins scientists investigating chemical modifications across the genomes of adult mice have discovered that DNA modifications in non-dividing brain cells, thought to be inherently stable, instead underwent large-scale dynamic changes as a result of stimulated brain activity. Their report, in the October issue of Nature Neuroscience, has major implications for treating psychiatric diseases, neurodegenerative disorders,...

2011-06-30 19:04:02

Results suggest novel approach to developing targeted cancer therapies Scientists at Fox Chase Cancer Center have discovered a new mechanism used by cells in the body to turn on silenced genes. This process is critical in preventing the development of cancer"”suggesting the possibility of new therapies that might target the specific changes underlying the disease. The findings will be published online in the journal Cell on June 30, 2011. The process investigated by Alfonso Bellacosa,...

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2010-01-07 08:28:06

The DNA contained within each of our cells is exactly the same, yet different types of cells "“ skin cells, heart cells, brain cells "“ perform very different functions. The ultimate fate of these cells is encoded not just in the DNA, but in a specific pattern of chemical modifications that overlay the DNA structure. These modifications, or epigenetic markers as they are called, are stably carried in our genomes -- except for at times when the cells change their fate, such as what...


Word of the Day
malpais
  • The ragged surface of a lava-flow.
'Malpais' translates from Spanish as 'bad land.'