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Latest DNA gyrase Stories

2011-11-30 10:50:15

In research at SRI International, scientists evaluating new drug targets against tuberculosis (TB) recently validated the preclinical effectiveness of a target that could rapidly eliminate infections and potentially shorten treatment time. The new drug target is a protein called DNA gyrase B, found in bacteria that cause TB infections. DNA gyrase is an enzyme consisting of two subunits: gyrase A and gyrase B. Although gyrase A is often the target of antibiotics, such as ciprofloxacin,...

2011-03-11 16:54:59

Scientists are collaborating on a new international research project to identify antibiotics that can kill tuberculosis and fight resistant strains. "We want to accelerate the discovery of new compounds that can be turned into effective drugs," said Professor Tony Maxwell from the John Innes Centre, a key player in "More Medicines for Tuberculosis", a new European research project. Two billion people are currently infected with TB and three million die every year. TB causes more deaths than...

2009-12-03 21:34:07

An antibiotic that binds to a well-established target in a novel and unexpected way could be the inspiration for designing new, more potent antibacterial drugs. "A completely new way to beat bacteria is an exciting find at a time when resistance to existing antibiotics is growing," said Professor Tony Maxwell from the John Innes Centre, lead author on the research to be published in Science. JIC is an institute of the BBSRC. The antibiotic molecule slots into pockets in the surface of a...


Word of the Day
snash
  • To talk saucily.
  • Insolent, opprobrious language; impertinent abuse.
This word is Scots in origin and probably imitative.