Latest DNA methylation Stories

IRVINE, Calif., May 8, 2013 /PRNewswire/ -- GeneTex, Inc., a leading manufacturer of antibodies and antibody-related reagents, is introducing a new mouse monoclonal antibody to the human Ten-Eleven Translocation 1 (TET1) protein. The discovery in 2009 (Tahiliani et al, 2009) that this enzyme can convert the DNA methylation mark 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC) helped to usher in a new field of research in epigenetics. Since then, it has become clear that TET1...

Food and environment can chemically alter your gene function and scientists have identified a gene that is consistently altered in obesity. The gene LY86 was among a group of 100 genes identified as likely contributors to obesity through genome-wide association studies comparing the DNA of thousands of obese and lean individuals, said Dr. Shaoyong Su, genetic epidemiologist at the Medical College of Georgia at Georgia Regents University. Su looked at progressively larger groups of obese...

At the 28th Annual EAU Congress currently ongoing in Milan until Tuesday, W. Tan and colleagues presented their study on neoadjuvant cisplatin-based chemotherapy which showed that epigenetic changes are potential key drivers in the development of chemo resistance in bladder cancer. Neoadjuvant cisplatin-based chemotherapy is recommended for patients with muscle invasive bladder cancer. Cisplatin-based regimes have similar efficacy with complete response in 30% a survival advantage if 16%...

Zymo Research, The Epigenetics Company, is changing the way we look at the human genome for markers of disease. With a newly expanded range of epigenetic services, Zymo Research helps scientists identify epigenetic alterations that could prove vital for disease diagnosis, prognosis, and the prediction of response to therapies. Irvine, CA (PRWEB) March 07, 2013 Zymo Research Corporation, a privately held company located in Irvine, California, has recently expanded its range of tools and...

Salk epigenetic findings may aid in crop production Scientists at the Salk Institute for Biological Studies have identified patterns of epigenomic diversity that not only allow plants to adapt to various environments, but could also benefit crop production and the study of human diseases. Published March 6 in Nature, the findings show that in addition to genetic diversity found in plants throughout the world, their epigenomic makeup is as varied as the environments in which they are...

A father's obesity is one factor that may influence his children's health and potentially raise their risk for diseases like cancer, according to new research from Duke Medicine. The study, which appears Feb. 6 in the journal BMC Medicine, is the first in humans to show that paternal obesity may alter a genetic mechanism in the next generation, suggesting that a father's lifestyle factors may be transmitted to his children. "Understanding the risks of the current Western lifestyle on...

Maternal diet and weight can impact their child's health even before birth – but so can a father's, shows a study published in BioMed Central's open access journal BMC Medicine. Hypomethylation of the gene coding for the Insulin-like growth factor 2, (IGF2),in newborns correlates to an increased risk of developing cancer later in life, and, for babies born to obese fathers, there is a decrease in the amount of DNA methylation of IGF2 in fetal cells isolated from cord blood. As part of...

Currently North America dominates with 40% of market share, followed by Europe with 36% (PRWEB) January 21, 2013 The report “Epigenetics Technology Market (Epigenomics, DNA Methylation, Histone Modifications, RNA interference, Cancer Therapeutics, Personalized Medicine) (2012 - 2017)” analyses the global epigenetics market by region, applications and epigenetic mechanisms with five year revenue forecasts. It also identifies the factors driving and restraining the global epigenetics...

DALLAS, January 15, 2013 /PRNewswire/ -- The report "Epigenetics Market (Epigenomics, DNA Methylation, Histone Modifications, RNA interference, Cancer Therapeutics, Personalized Medicine) (2012 - 2017)" analyses the global epigenetics market by region, applications and epigenetic mechanisms with five year revenue forecasts. It also identifies the factors driving and restraining the global epigenetics market with analysis of trends, opportunities and challenges. The...

Degree of abnormal DNA methylation predicts outcomes Think of the epigenome like a giant musical mixing board, turning up or down the expression of various genes. A University of Colorado Cancer Center study published today in the journal PLOS Genetics shows that in cancer, not only can genes themselves go bad, but abnormal changes in the epigenetic mixing board can unfortunately change the expression of these genes. Researchers hope to play the role of sound engineers, controlling these...