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Latest DNA methylation Stories

2010-11-10 12:42:26

DNA methylation plays an important role in many processes such as animal development, X-chromosome inactivation, and carcinogenesis. Understanding the mechanisms and functions of DNA methylation and how it varies from tissue to tissue and between individuals will have profound implications for human health and disease. A team of Chinese researchers decoded the essentially complete methylome (an inventory of all the bases that are methylated) of the human genome using peripheral blood...

2010-10-14 16:25:00

IPSWICH, Mass., Oct. 14 /PRNewswire/ -- New England Biolabs (NEB) has launched a suite of new and validated products designed to simplify DNA methylation analysis for epigenetics researchers. These enzyme-based solutions address some of the challenges of the current methods, including the lack of a reproducible method for the analysis and quantitation of 5-hydroxymethlcytosine (5-hmC) in the epigenome. (Logo: http://photos.prnewswire.com/prnh/20090921/NE79207LOGO-b ) (Logo:...

2010-10-11 13:16:46

For the first time, UK scientists have reported direct evidence that taking up smoking results in epigenetic changes associated with the development of cancer. The results were reported at the 35th Congress of the European Society for Medical Oncology (ESMO) in Milan, Italy. The link between smoking and cancer has been established for decades, explained Dr Yuk Ting Ma from the Cancer Research UK Institute of Cancer Studies, Birmingham, who presented the results. Smoking is the single biggest...

2010-10-04 16:58:18

Post-translational modifications of histones play an important role in regulating chromatin dynamics and function. One such modification, methylation, is involved in the regulation of the epigenetic program of a cell, determining chromatin structure, and regulating transcription. Methylation of histones occurs on both lysine and arginine residues, and until recently, was thought to be an irreversible process. The recent discovery of histone demethylases revealed that histone methylation is...

2010-09-27 07:00:00

SYDNEY, Sept. 27 /PRNewswire/ -- Clinical Genomics Pty. Ltd (Sydney, Australia) and The Garvan Institute of Medical Research (Sydney, Australia) today announced that they have entered into a license agreement in relation to novel biomarkers discovered by scientists at the Garvan Institute. Under the terms of the agreement, Clinical Genomics obtains worldwide exclusive rights to the Garvan's proprietary cancer associated methylation DNA biomarkers for the diagnosis and or treatment of...

2010-09-22 18:37:00

LIEGE, Belgium, Sept. 22 /PRNewswire/ -- Diagenode announced today that it has released two additional 5-hmC antibodies to complement its original 5-hmC (rat) monoclonal antibody. The two new 5-hmC monoclonal antibody (mouse) and polyclonal antibody (rabbit) antibodies give researchers additional choices for enriching and analyzing 5-hmC in their methylation studies. (Photo: http://photos.prnewswire.com/prnh/20100922/NY69887 ) (Photo: http://www.newscom.com/cgi-bin/prnh/20100922/NY69887 )...

2010-09-20 16:32:24

Colon cancer is the second most common cancer in the United States and causes more than 50,000 deaths each year. It has been known for some time that mutations in the APC gene occur in more than 85 percent of all sporadic colon cancers. Now researchers at Huntsman Cancer Institute at the University of Utah demonstrate in a study featured today in Cell the mechanism by which mutation of the APC gene affects a cellular process known as DNA methylation. DNA methylation is a chemical modification...

2010-09-15 19:16:17

Johns Hopkins scientists who specialize in unconventional hunts for genetic information outside nuclear DNA sequences have bagged a weighty quarry "” 13 genes linked to human body mass. The experiments screened the so-called epigenome for key information that cells remember other than the DNA code itself and may have serious implications for preventing and treating obesity, the investigators say. "Some of the genes we found are in regions of the genome previously suspected but not...

2010-09-15 15:41:00

IPSWICH, Mass., Sept. 15 /PRNewswire/ -- New England Biolabs (NEB) has announced that it has received fast track SBIR funding of $1.22 million to fund the research and development of novel enzymatic reagents for epigenetic studies. (Logo: http://photos.prnewswire.com/prnh/20090921/NE79207LOGO-b ) (Logo: http://www.newscom.com/cgi-bin/prnh/20090921/NE79207LOGO-b ) New England Biolabs is committed to developing tools that advance epigenetics research and discovery, and offers a growing...

2010-08-17 16:49:41

Potential application for stem cell therapies Having charted the occurrence of a common chemical change that takes place while stem cells decide their fates and progress from precursor to progeny, a Johns Hopkins-led team of scientists has produced the first-ever epigenetic landscape map for tissue differentiation. The details of this collaborative study between Johns Hopkins, Stanford and Harvard appear August 15 in the early online publication of Nature. The researchers, using blood-forming...


Word of the Day
siliqua
  • A Roman unit of weight, 1⁄1728 of a pound.
  • A weight of four grains used in weighing gold and precious stones; a carat.
  • In anatomy, a formation suggesting a husk or pod.
  • The lowest unit in the Roman coinage, the twenty-fourth part of a solidus.
  • A coin of base silver of the Gothic and Lombard kings of Italy.
'Siliqua' comes from a Latin word meaning 'a pod.'
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