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Latest DNA methylation Stories

2010-04-16 08:26:27

Study identifies patients with longer-than-expected survival times A study conducted by a collaborative team led by researchers from the University of Southern California (USC) may lead to better insight into the clinical outcome for some patients with a particularly aggressive type of brain cancer. The research may also provide a framework for development of targeted drug treatments. The research by The Cancer Genome Atlas (TCGA), published online today in the journal Cancer Cell, used...

2010-04-08 08:51:56

A University of British Columbia doctoral candidate has discovered a previously unknown mechanism for silencing retroviruses, segments of genetic material that can lead to fatal mutations in a cell's DNA. The findings, published April 7 in the journal Nature, could lead to new cancer treatments that kill only tumor cells and leave healthy surrounding tissue unharmed. Danny Leung, a 27-year-old graduate student in the laboratory of Asst. Prof. Matthew Lorincz in the Dept. of Medical Genetics,...

2010-02-25 13:44:55

A paper published online today in Molecular Cell proposes that Methyl CpG binding protein 2 (MeCP2) impacts the entire genome in neurons, rather than acting as a regulator of specific genes. Mutations in MeCP2 cause the autism spectrum disorder Rett Syndrome as well as some cases of neuropsychiatric problems including autism, schizophrenia and learning disabilities. The discovery of MeCP2's global reach was made in the laboratory of Adrian Bird, Ph.D. of the University of Edinburgh. Bird's...

2010-02-23 11:09:24

Scientists from Sydney's Garvan Institute of Medical Research have published a paper, online Feb. 22 in Nature Cell Biology, describing gene expression in a prostate cancer cell: more sweeping, more targeted and more complex than we could ever have imagined, even five years ago. The study shows that changes within the prostate cancer cell 'epigenome' (biochemical processes that target DNA and affect gene expression) alter the expression of many genes, silencing their expression within large...

2010-02-21 11:12:08

News briefing at 2010 AAAS meeting More than three million children have been born as a result of assisted reproductive technologies since the birth of the first "test tube baby" in 1978. While the majority of these children are healthy and normal, as a group they are at greater risk of certain kinds of birth defects and being low birth weight, which is associated with obesity, hypertension and type 2 diabetes later in life. Carmen Sapienza, a geneticist at Temple University School of...

2010-02-16 09:45:00

SPARTA, N.J. and LIEGE, Belgium, Feb. 16 /PRNewswire/ -- Diagenode, an innovative leader providing products and technologies for epigenetics, genomics and diagnostics, and the only provider of complete epigenetics solutions, announced today the launch of its innovative platform for automated epigenetics assays, the SX-8G IP-Star(TM) system ("IP-Star(TM)). The introduction follows the successful completion of six independent collaborations with high-profile research laboratories in the...

2010-02-13 08:29:32

Researchers from the Institute of Psychiatry (IoP), King's College London, have identified numerous novel regions of the genome where the chemical modifications involved in controlling gene expression are influenced by either genetic variation or the parental origin of that particular stretch of DNA. This contradicts previous assumptions that epigenetic signals are generally equal across both copies of a given region of the genome, except at a small number of known imprinted genes. Sequencing...

2010-02-10 08:58:28

Gastric cancer, one of the most common types of cancer, is associated with high mortality rates. In the last decades, a decrease in the worldwide incidence has been observed with some changes in the therapeutic and diagnostic options. However, the prognosis for this disease still remains poor, mainly when the diagnosis is performed at advanced stages. The therapy most effective is still surgical resection and in a significant number of cases, especially in the advanced stage, it is only...

2010-02-04 12:02:48

Billions of data points provide big picture of 'human epigenome' during critical developmental window Scientists at The Scripps Research Institute and The Genome Institute of Singapore (GIS) led an international effort to build a map that shows in detail how the human genome is modified during embryonic development. This detailed mapping is a significant move towards the success of targeted differentiation of stem cells into specific organs, which is a crucial consideration for stem cell...

2010-02-03 22:26:38

Billions of data points provide big picture of 'human epigenome' during critical developmental window Scientists at The Genome Institute of Singapore (GIS) and The Scripps Research Institute (TSRI) led an international effort to build a map that shows in detail how the human genome is modified during embryonic development. This detailed mapping is a significant move towards the success of targeted differentiation of stem cells into specific organs, which is a crucial consideration for stem...


Word of the Day
abrosia
  • Wasting away as a result of abstinence from food.
The word 'abrosia' comes from a Greek roots meaning 'not' and 'eating'.