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Latest DNA methylation Stories

2009-11-30 16:30:07

Researchers at Uppsala University and University Children's Hospital in Uppsala have devised powerful new tools for typing cells from children with acute lymphatic leukemia and for prediction of how children with leukemia will respond to chemotherapy. The study was recently published in electronic form by the prestigious hematological journal Blood. Acute leukemia is the most common form of childhood cancer. The new study shows that DNA methylation is a promising tool for predicting disease...

2009-11-05 12:54:04

The same genes that are chemically altered during normal cell differentiation, as well as when normal cells become cancer cells, are also changed in stem cells that scientists derive from adult cells, according to new research from Johns Hopkins and Harvard. Although genetically identical to the mature body cells from which they are derived, induced pluripotent stem cells (iPSCs) are notably special in their ability to self-renew and differentiate into all kinds of cells. And now scientists...

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2009-10-15 06:25:00

Despite the fact that the human genome sequence lists nearly every single DNA base of the roughly 3 billion bases that make up a human genome, it has remained a biological mystery as to how its function is regulated. Now, scientists from the Salk Institute have revealed the first detailed map of the human epigenome, which is the network of chemical switches that regulates activation of human genes. The human genome was decoded almost 10 years ago, which plainly showed the building blocks of...

2009-10-12 07:00:00

ST. LOUIS, Oct. 12 /PRNewswire/ -- Orion Genomics today announced that it has entered into a multi-year collaboration and license agreement with the molecular diagnostics unit of Novartis Pharma AG. Under the collaboration, the parties seek to discover novel epigenetic biomarkers, and both parties have rights to independently develop and commercialize diagnostic products in their respective fields. Under the terms of the agreement, Orion Genomics also grants Novartis non-exclusive...

2009-10-08 09:44:16

Researchers at Henry Ford Hospital have identified tumor-suppressing genes that may provide a more accurate diagnosis of disease stage and survival for laryngeal cancer patients than current standards. The study finds genetic abnormalities of the ESR1(estrogen specific receptor 1) gene and the HIC1 (hypermethylated in cancer 1) gene are predictors of late-stage laryngeal cancer and shorter survival, respectively, for patients with the disease. Study results was presented Wednesday, Oct. 7 at...

2009-10-06 13:36:19

During cell division, whether hematopoietic stem cells (HSCs) will develop into new stem cells (self-renewal) or differentiate into other blood cells depends on a chemical process called DNA methylation. These were the findings of researchers at the laboratory of Dr. Frank Rosenbauer of the Max Delbrck Center for Molecular Medicine (MDC) Berlin-Buch in cooperation with the laboratory of Professor Sten Eirik W. Jacobsen (Lund University, Sweden and the University of Oxford, England)....

2009-10-05 06:10:00

A Henry Ford Hospital study has identified 231 new genes associated with head and neck cancer, one of the most deadly cancers responsible for 2.1 percent of all cancer deaths in the United States. Previously, only 33 genes were reported associated with head and neck cancer. "These new genes should advance selection of head and neck-specific gene targets, opening the door to promising new molecular strategies for the early detection and treatment of head and neck cancer," says study lead...

2009-10-05 01:30:00

LAUSANNE, Switzerland, October 5 /PRNewswire/ -- Debiopharm Group (Debiopharm), a Swiss-based global biopharmaceutical group of companies with a focus on the development of prescription drugs that target unmet medical needs, and the Japanese Cancer Association (JCA) presented 'The JCA-Mauvernay Award' to Dr Toshikazu Ushijima from the National Cancer Center Research Institute in Tokyo, for his outstanding and innovative research in basic science in the "epigenetic field for...

2009-09-30 14:00:00

NEW YORK, Sept. 30 /PRNewswire/ -- Epigentek Group Inc. today announced that it released the SuperSense(TM) Methylated DNA Quantification Kit to complete its line of methylated DNA quantification products (http://www.epigentek.com/catalog/dna-methylation-quantification-c-21_48.html). The SuperSense(TM) kit fluorometrically measures global DNA methylation shifts. This new tool complements the company's flagship product and colorimetric version of quantifying methylated DNA, the...

2009-09-21 13:27:51

Two new blood tests can aid in the early identification of patients with gastrointestinal cancers, researchers in Belgium have found. Dr. Joost Louwagie of OncoMethylome Sciences, a company in Liege, Belgium, said the scientists collected blood before surgery from 193 patients known to have colorectal cancer, as well as from 688 controls undergoing colonoscopy for cancer screening. DNA was extracted from the blood plasma and tested for the presence of DNA methylation of specific genes. DNA...


Word of the Day
sough
  • A murmuring sound; a rushing or whistling sound, like that of the wind; a deep sigh.
  • A gentle breeze; a waft; a breath.
  • Any rumor that engages general attention.
  • A cant or whining mode of speaking, especially in preaching or praying; the chant or recitative characteristic of the old Presbyterians in Scotland.
  • To make a rushing, whistling, or sighing sound; emit a hollow murmur; murmur or sigh like the wind.
  • To breathe in or as in sleep.
  • To utter in a whining or monotonous tone.
According to the OED, from the 16th century, this word is 'almost exclusively Scots and northern dialect until adopted in general literary use in the 19th.'
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