Latest DNA methylation Stories
It's widely accepted that molecular mechanisms mediating epigenetics include DNA methylation and histone modifications, but a team from Thomas Jefferson University has evidence to the contrary regarding the role of histone modifications.
Chimpanzees rarely get cancer, or a variety of other diseases that commonly arise in humans, but their genomic DNA sequence is nearly identical to ours.
Over the last 50 years, the spotting of newborn's blood onto filter paper for disease screening, called Guthrie cards, has become so routine that since 2000, more than 90% of newborns in the United States have had Guthrie cards created.
Salk study finds stress triggers widespread epigenetic changes that aid in disease resistance
Your genes determine much about you, but environment can have a strong influence on your genes even before birth, with consequences that can last a lifetime.
In what could be a breakthrough in the practical application of epigenetic science, U.K. scientists used human tissue samples to discover that those with osteoarthritis have a signature epigenetic change (DNA methylation) responsible for switching on and off a gene that produces a destructive enzyme called MMP13.
It's not just our DNA that makes us susceptible to disease and influences its impact and outcome.
University of Texas Medical Branch at Galveston researchers have found a surprising connection between a key DNA-repair process and a cellular signaling network linked to aging, heart disease, cancer and other chronic conditions.
In a highlighted paper published online in Nature Communications, researchers from Sichuan Agricultural University and BGI, the world's largest genomics organization, reported the atlas of DNA methylomes in porcine adipose and muscle tissues, providing a valuable epigenomic source for obesity prediction and prevention as well as boosting the further development of pig as a model animal for human obesity research.
Alterations to the "on-off" switches of genes occur early in the development of prostate cancer and could be used as biomarkers to detect the disease months or even years earlier than current approaches, a Mayo Clinic study has found.
- A pivoted catch designed to fall into a notch on a ratchet wheel so as to allow movement in only one direction (e.g. on a windlass or in a clock mechanism), or alternatively to move the wheel in one direction.