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Latest DNA methylation Stories

2011-12-07 20:02:13

In the bone marrow, blood-forming (hematopoietic) stem cells become one of the myriad kinds of blood cells in the body or they can self-renew, maintaining that pool. However, the lack or mutation of a gene for an enzyme called Dnmt3a (DNA methyltransferase 3a) results in an abundance of stem cells and a lack of blood cells, said a consortium of researchers led by those at in the Stem Cells and Regenerative Medicine Center at Baylor College of Medicine in a report online in the journal...

2011-11-29 10:59:52

A University of Cambridge study, which set out to investigate DNA methylation in the human heart and the 'missing link' between our lifestyle and our health, has now mapped the link in detail across the entire human genome. The new data collected greatly benefits a field that is still in its scientific infancy and is a significant leap ahead of where the researchers were, even 18 months ago. Researcher Roger Foo explains: "By going wider and scanning the genome in greater detail this...

2011-11-22 11:15:24

Smoking during pregnancy profoundly changes both DNA and the expression of placental genes, a possible factor in physical changes that can last a lifetime, said researchers from Baylor College of Medicine in a report in the current edition of the journal Epigenetics. In a study that correlated changes in DNA methylation (a chemical change that affects the level of gene expression) to changes in gene expression across the genome of the placenta (the small ovoid organ that nourishes the...

2011-11-10 15:26:29

COMBINATION 'EPIGENETIC' THERAPY MAY RESTORE ANTI-CANCER GENE ACTIVITY IN LATE-STAGE LUNG CANCER PATIENTS Small clinical trial shows promising positive effects A new type of therapy aimed at reversing the gene-silencing that promotes cancer-cell growth has shown promising results in a small clinical trial conducted by researchers at the Johns Hopkins Kimmel Cancer Center.  Forty-five late-stage lung cancer patients who received a two-drug combination designed to restore anti-cancer...

2011-10-03 15:30:12

Finding has implications for treatment of wide range of diseases Johns Hopkins scientists investigating chemical modifications across the genomes of adult mice have discovered that DNA modifications in non-dividing brain cells, thought to be inherently stable, instead underwent large-scale dynamic changes as a result of stimulated brain activity. Their report, in the October issue of Nature Neuroscience, has major implications for treating psychiatric diseases, neurodegenerative disorders,...

2011-09-27 11:20:26

Scientists at Cold Spring Harbor Laboratory (CSHL) and the University of Southern California (USC) have uncovered intriguing new evidence helping to explain one of the ways in which a stem cell's fate can be determined. The new data show how the "marking" of DNA sequences by groups of methyl molecules — a process called methylation — can influence the type of cell a stem cell will become. The cellular maturation process, called differentiation, has long been thought to be...

Are Genes Our Destiny
2011-09-18 06:30:55

  Salk scientists discover 'hidden' code in DNA evolves more rapidly than genetic code A "hidden" code linked to the DNA of plants allows them to develop and pass down new biological traits far more rapidly than previously thought, according to the findings of a groundbreaking study by researchers at the Salk Institute for Biological Studies. The study, published Sept. 16 in the journal Science, provides the first evidence that an organism's "epigenetic" code - an extra layer of...

2011-08-10 18:08:19

Mariusz A. Wasik, MD, professor of Pathology and Laboratory Medicine, and Qian Zhang, MD, PhD, research assistant professor, both from the Perelman School of Medicine at the University of Pennsylvania, and their colleagues, found that a cancer-causing fusion protein works by silencing the tumor suppressor gene IL-2R common gamma-chain (IL-2RÃŽ³). The results, which appeared in a recent Proceedings of the National Academy of Sciences, suggest news targets for lymphoma and...

2011-07-23 00:00:41

IVF research led by New Hampshire Reproductive Center fertility doctor, Kristen P Wright, MD, indicates IVF process effects DNA methylation associated with two syndromes (PRWEB) July 22, 2011 Since the birth of the first IVF baby in 1978, more than 3 million children have been born worldwide following IVF treatments. Numerous studies have been conducted to assess the overall health of children born after IVF. The majority of these studies on the safety of IVF have been reassuring....


Word of the Day
Cthulhu
  • A gigantic fictional humanoid alien god being described with a head resembling an octopus and dragon wings and claws, around whom an insane cult developed.
  • Pertaining to the mythos of Cthulhu and additional otherworldly beings created by H. P. Lovecraft or inspired by his writings and imitators.
This word was invented in 1926 by H.P. Lovecraft for his short story, 'The Call of Cthulhu.' 'Cthulhu' may be based on the word 'chthonic,' which in Greek mythology refers to the underworld.
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