Quantcast
Last updated on April 20, 2014 at 14:04 EDT

Latest DNA methylation Stories

2011-05-18 14:18:29

Children whose mothers or grandmothers smoked during pregnancy are at increased risk of asthma in childhood, but the underlying causes of this are not well understood. Now a new study indicates changes in a process called DNA methylation that occurs before birth may be a root cause. The study will be presented at the ATS 2011 International Conference. DNA methylation is a process that can alter a gene's usual function. These altered genes can be passed along from parent to child. In this...

2011-05-12 22:14:40

Discovery, which has implications for cancer, explains why some genes are silenced Japanese and U.S. scientists in the young field of epigenetics Thursday reported a rationale as to how specific genes are silenced and others are not. Because this effect can be reversed, it may be possible to devise therapies for cancer and other diseases using this information. The NOVA U.S. public television program described epigenetics as "The Ghost In Your Genes." It is the study of changes in gene...

2011-04-20 21:26:46

Exposure to air pollution early in life and when a woman gives birth to her first child may alter her DNA and may be associated with premenopausal breast cancer later in life, researchers at the University at Buffalo have shown. The findings indicated that higher air pollution exposure at birth may alter DNA methylation, which may increase levels of E-cadherin, a protein important to the adhesion of cells, a function that plays an essential role in maintaining a stable cellular environment...

2011-04-05 15:15:00

IPSWICH, Mass. and SAN DIEGO, April 5, 2011 /PRNewswire/ -- New England Biolabs, Inc. (NEB) and Sequenom, Inc. (NASDAQ: SQNM) jointly announce that they have signed a licensing and co-marketing agreement to commercialize research tools for epigenetics. This agreement is the result of a research collaboration between the two companies that has culminated in the development of the EpiMark(TM) Methylated DNA Enrichment Kit from NEB. (Logo:...

2011-02-09 15:58:00

IPSWICH, Mass., Feb. 9, 2011 /PRNewswire/ -- New England Biolabs (NEB) has published a video protocol with the Journal of Visualized Experiments (JoVE) for the EpiMark(TM) 5-mC and 5-hmC Analysis Kit, one of a suite of new and validated products designed to simplify DNA methylation analysis for epigenetics researchers. The protocol describes a 3-step, PCR-based assay to identify and quantitate 5-methylcytosine (5-mC) and 5-hydroxymethylcytosine (5-hmC) within a specific DNA locus....

2011-02-02 20:32:41

Reprogramming adult cells to recapture their youthful "can-do-it-all" attitude appears to leave an indelible mark, found researchers at the Salk Institute for Biological Studies. When the team, led by Joseph Ecker, PhD., a professor in the Genomic Analysis Laboratory, scoured the epigenomes of so-called induced pluripotent stem cells base by base, they found a consistent pattern of reprogramming errors. What's more, these incompletely or inadequately reprogrammed hotspots are maintained when...

2011-02-01 17:27:44

Think of your genome as a dynamic outdoor sculpture. Its shape is, of course, influenced by its structural underpinnings "“ the double helix containing phosphate and two chains of nucleotides attached to a sugar called deoxyribose. These chains wind around each other, linked by hydrogen bonds between the specific bases "“ adenine to thymine and cytosine to guanine. But forces outside your sculpture also act on it. If it were really outside, the forces would be wind, rain, sunlight...

2011-01-24 15:44:16

A new study shows that a test of biomarkers for DNA methylation is technically feasible and could aid in earlier, more precise diagnosis of melanoma. In a paper that appeared online last week in the journal Pigment Cell & Melanoma Research, a team of UNC researchers tested whether DNA methylation profiling could be accomplished on melanoma and mole tissues that had been preserved in fixatives for typical pathology examination after biopsy. They found that results on tissues prepared in...

2011-01-20 16:23:15

Fat appears to associate with some distinctive chemical changes in the DNA "“ a finding that may help explain why obesity can increase the risk for chronic problems such as cardiovascular disease and diabetes, researchers report. The finding, published in BMC Medicine, may one day help identify those at risk and reduce it, according to Dr. Xiaoling Wang, genetic epidemiologist at the Medical College of Georgia's Georgia Prevention Institute. "Losing fat is very difficult; we know that....

2011-01-03 08:24:20

(Ivanhoe Newswire) "“ New insight into the biology of many kinds of less aggressive but lethal brain tumors, or gliomas, opens up a wide variety of possibilities for new therapies, according to this study. The researchers describe how genetic mutation leads to an abnormal metabolic process in the tumors that could be targeted by drug makers."What this tells you is that there are some forms of tumors with a fundamentally altered process," Karl Kelsey, a professor of pathology and...