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Last updated on April 23, 2014 at 16:13 EDT

Latest DNA methyltransferase Stories

2014-01-27 04:21:37

DUBLIN, January 27, 2014 /PRNewswire/ -- Research and Markets ( http://www.researchandmarkets.com/research/g3pk2m/epigenetics_drugs) has announced the addition of the "2013 Report on the International Epigenetics Drugs and Diagnostic Technologies Market - Trends And Forecasts to 2018" [http://www.researchandmarkets.com/research/g3pk2m/epigenetics_drugs ] report to their offering. (Logo: http://photos.prnewswire.com/prnh/20130307/600769 ) "2013 Report on the...

2013-10-07 13:18:53

This press release is in support of a presentation by Dr. Daniel van den Hove on Sunday Oct. 6 at the 26th ECNP Congress in Barcelona, Spain Increasing evidence suggests that epigenetic regulation is associated with the pathogenesis of Alzheimer's disease (AD) and targeting it may one day lead to novel diagnostic and therapeutic strategies, research suggests. Scientists at The School for Mental Health and Neuroscience at Maastricht University, the Netherlands, have been performing...

2013-06-26 08:30:19

ALBANY, New York, June 26, 2013 /PRNewswire/ -- According to a new market report published by Transparency Market Research (http://www.transparencymarketresearch.com) "Epigenetics Drugs and Diagnostic Technologies Market - Global Industry Analysis, Size, Share, Growth, Trends and Forecast, 2012 - 2018," the global epigenetic drugs and diagnostic technologies market was valued at USD 1.6 billion in 2011 and is estimated to reach a market worth USD 5.7 billion in 2018 at a CAGR...

2013-05-08 12:28:56

IRVINE, Calif., May 8, 2013 /PRNewswire/ -- GeneTex, Inc., a leading manufacturer of antibodies and antibody-related reagents, is introducing a new mouse monoclonal antibody to the human Ten-Eleven Translocation 1 (TET1) protein. The discovery in 2009 (Tahiliani et al, 2009) that this enzyme can convert the DNA methylation mark 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC) helped to usher in a new field of research in epigenetics. Since then, it has become clear that TET1 and its...

2012-11-08 16:27:22

IPSWICH, Mass., Nov. 8, 2012 /PRNewswire/ -- New England Biolabs (NEB) has recently received a $640,000 Phase II Small Business Innovation Research (SBIR) grant to expand its research and product development of novel enzymatic tools for epigenetic analysis. This latest grant adds to the more than $1.1 million of SBIR funds awarded for this research since 2009. (Logo: http://photos.prnewswire.com/prnh/20090921/NE79207LOGO-b ) Since its establishment in 1974, NEB has been dedicated to the...

2012-11-02 14:36:43

Caltech-led team discovers enzyme responsible for neural crest cell development During the early developmental stages of vertebrates–animals that have a backbone and spinal column, including humans–cells undergo extensive rearrangements, and some cells migrate over large distances to populate particular areas and assume novel roles as differentiated cell types. Understanding how and when such cells switch their purpose in an embryo is an important and complex goal for...

2012-01-23 10:47:41

UT MD Anderson researchers expose molecular connection between inflammation, methylation Chronic inflammation combines with DNA methylation, a process that shuts down cancer-fighting genes, to promote development of colorectal cancer, scientists at The University of Texas MD Anderson Cancer Center report today in the advance online publication of the journal Nature Medicine. The team's connection of these two separate influences eventually may lead to better combination therapies for...

2011-09-27 11:20:26

Scientists at Cold Spring Harbor Laboratory (CSHL) and the University of Southern California (USC) have uncovered intriguing new evidence helping to explain one of the ways in which a stem cell's fate can be determined. The new data show how the "marking" of DNA sequences by groups of methyl molecules — a process called methylation — can influence the type of cell a stem cell will become. The cellular maturation process, called differentiation, has long been thought to be...

2011-05-02 16:30:51

Mayo Clinic researchers have discovered two mutations responsible for a devastating neurological condition they first identified 15 years ago. The researchers say their study -- appearing in Nature Genetics -- has revealed a new neural pathway that may help understand a variety of similar conditions. "We were able to do this now because of Next Generation genomic sequencing technology," says Christopher Klein, M.D., Mayo Clinic neurologist and lead author of the study. "We also had the...

2010-06-04 14:23:25

A gene shown to play a role in the aging process appears to play a role in the regulation of the differentiation of embryonic stem cells, according to researchers from the Center for Stem Cell Biology and Regenerative Medicine and the Department of Medicine at Thomas Jefferson University. In the study, published online in the journal Aging Cell, the researchers identified a protein interaction that controls the silencing of Oct4, a key transcription factor that is critical to ensuring that...