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Latest DNA repair Stories

Peng Mao DNA repair
2014-08-21 02:30:00

Becky Phillips, Washington State University Scientists at Washington State University have identified a crucial step in DNA repair that could lead to targeted gene therapy for hereditary diseases such as “children of the moon” and a common form of colon cancer. Such disorders are caused by faulty DNA repair systems that increase the risk for cancer and other conditions. The findings are published in this week’s Proceedings of the National Academy of Sciences. The study was funded...

2014-06-09 14:30:56

University of North Carolina Health Care The discovery, from the lab of Brian Strahl, Ph.D., offers insights for the creation of better, more targeted therapies for various forms of cancer Twelve years ago, UNC School of Medicine researcher Brian Strahl, PhD, found that a protein called Set2 plays a role in how yeast genes are expressed – specifically how DNA gets transcribed into messenger RNA. Now his lab has found that Set2 is also a major player in DNA repair, a complicated and...

2014-05-28 08:51:16

University of Zurich DNA damage repair is highly complex. UZH researchers have now discovered another piece in the puzzle for the removal of extremely dangerous DNA lesions. Faithful and efficient repair of so-called crosslinks requires a collaboration between a specific signalling and repair protein. As crosslink-inducing agents are used in chemotherapy, the new insights are also important for the development of better anti-cancer treatment strategies. Environmental influences such as...

2014-05-07 08:54:14

Each time a human cell divides, it must first make a copy of its 46 chromosomes to serve as an instruction manual for the new cell. Normally, this process goes off without a hitch. But from time to time, the information isn't copied and collated properly, leaving gaps or breaks that the cell has to carefully combine back together. Researchers have long recognized that some regions of the chromosome,called "fragile sites," are more prone to breakage and can be a breeding ground for human...

2014-04-18 15:52:50

Finding could influence cancer care and regenerative medicine An international team led by researchers at UC Davis has shown that the cyclin B1/Cdk1 protein complex, which plays a key role in cell division, also boosts the mitochondrial activity to power that process. This is the first time the complex has been shown to perform both jobs. This newfound ability could make cyclin B1/Cdk1 an excellent target to control cellular energy production, potentially advancing cancer care and...

2014-04-04 12:23:54

These genes could explain why some women with high-risk mutations suffer from cancer while others do not Today we know that women carrying BCRA1 and BCRA2 gene mutations have a 43% to 88% risk of developing from breast cancer before the age of 70. Taking critical decisions such as opting for preventive surgery when the risk bracket is so wide is not easy. Spanish National Cancer Research Centre (CNIO) researchers are conducting a study that will contribute towards giving every woman far...

Studying The Effects Of Microgravity And Radiation On Human Cells
2014-02-28 08:41:19

Lawrence LeBlond for redOrbit.com - Your Universe Online Life aboard the International Space Station (ISS) may seem like a carefree existence, but a wealth of evidence has proven otherwise. Years of research shows that the effects of microgravity wreaks havoc on the human body. However, microgravity isn’t the only thing that astronauts need to worry about in space. Going into space means exposure to radiation, which is known to damage our DNA. And when DNA tries to repair itself,...

2014-02-13 23:22:26

The DNA health monitoring citizen science campaign launched by Exogen Biotechnology, Inc. exceeded its crowdfunding goal on Indiegogo by raising over $55,000 from US donors within two weeks. The biotech startup is now expanding their campaign internationally to look at differences in DNA damage across different countries and cultures around the world. Berkeley, CALIFORNIA (PRWEB) February 13, 2014 Exogen Biotechnology, Inc. the latest startup company to spin off from technology developed...

How Does A Shape-shifting DNA-repair Machine Fight Cancer?
2014-02-04 12:27:58

Lawrence Berkeley National Laboratory Berkeley Lab’s Advanced Light Source reveals inner-workings of essential protein found throughout life. Maybe you’ve seen the movies or played with toy Transformers, those shape-shifting machines that morph in response to whatever challenge they face. It turns out that DNA-repair machines in your cells use a similar approach to fight cancer and other diseases, according to research led by scientists from the U.S. Department of Energy’s...

2014-01-10 23:22:58

Wayland Baptist University's Jessica Kenneson, along with professor Robert Moore, have developed an imaging device that is doing the work of several much more expensive devices. Kenneson is using it for her research on tuberculosis. Plainview, TX (PRWEB) January 10, 2014 If necessity is indeed the mother of invention, freshman exuberance certainly lends a hand. Just ask Jessica Kenneson. Kenneson is a junior chemistry/molecular biology double major at Wayland Baptist University and...


Word of the Day
malpais
  • The ragged surface of a lava-flow.
'Malpais' translates from Spanish as 'bad land.'