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Latest DNA repair Stories

2011-12-23 01:07:20

In eukaryotes — the group of organisms that include humans — a key to survival is the ability of certain proteins to quickly and accurately repair genetic errors that occur when DNA is replicated to make new cells. In a paper published in the December 23, 2011 issue of the journal Science, researchers at the Ludwig Institute for Cancer Research and the University of California, San Diego School of Medicine have solved part of the mystery of how these proteins do their job, a...

2011-12-20 18:30:44

Berkeley Lab Researchers Find Evidence Suggesting Risk May Not Be Proportional to Dose at Low Dose Levels Researchers with the U.S. Department of Energy (DOE)´s Lawrence Berkeley National Laboratory (Berkeley Lab), through a combination of time-lapse live imaging and mathematical modeling of a special line of human breast cells, have found evidence to suggest that for low dose levels of ionizing radiation, cancer risks may not be directly proportional to dose. This contradicts the...

2011-12-12 23:35:09

Looking for ways to halt the uncontrolled growth of cancer cells, scientists at Johns Hopkins have found that a new class of drugs, called PARP inhibitors, may block the ability of pre-leukemic cells to repair broken bits of their own DNA, causing these cells to self-destruct. Results of their experiments, expected to be presented at the 53rd Annual Meeting of the American Society of Hematology in San Diego, Dec. 12, have already prompted clinical trials of the drugs in patients with...

2011-12-06 08:00:00

The BioSciences Magazine EurekaMag.com publishes insights into specific topics in the biological sciences. The latest articles cover Cell Division which is the process by which parent cells divide into daughter cells, DNA Replication as the process of copying DNA during Cell Division, and Cellular Respiration which is a set of metabolic reactions by which cells of living organisms gain energy. Mannheim, Germany (PRWEB) December 06, 2011 The BioSciences Magazine EurekaMag.com covers a wide...

2011-12-01 22:11:14

Shortening end caps on chromosomes in human cervical cancer cells disrupts DNA repair signaling, increases the cells´ sensitivity to radiation treatment and kills them more quickly, according to a study in Cancer Prevention Research. Researchers would to like see their laboratory findings — published in the journal´s Dec. 5 print edition — lead to safer, more effective combination therapies for hard-to-treat pediatric brain cancers like medulloblastoma and high-grade...

2011-11-05 01:23:40

Working with lab cultures and mice, Johns Hopkins scientists have found that a strain of the common gut pathogen Bacteroides fragilis causes colon inflammation and increases activity of a gene called spermine oxidase (SMO) in the intestine. The effect is to expose the gut to hydrogen peroxide — the caustic, germ-fighting substance found in many medicine cabinets -- and cause DNA damage, contributing to the formation of colon tumors, say the scientists. "Our data suggest that the SMO...

2011-11-04 21:25:09

Scientists of the German Cancer Research Center have discovered an alternative mechanism for the extension of the telomere repeat sequence by DNA repair enzymes. The ends of the chromosomes, the telomeres, are repetitive DNA sequences that shorten every time a cell divides during the process of duplicating its genome. Once the telomeres become very short the cell stops dividing. Thus, telomeres work like a cellular clock that keeps an eye on the number of cell divisions. And once the...

2011-11-02 08:52:13

Researchers have identified a potential drug therapy for a premature ageing disease that affects children causing them to age up to eight times as fast as the usual rate. The study is the first to outline how to limit and repair DNA damage defects in cells and could provide a model for understanding processes that cause us to age. The findings could have significant benefits, such as reducing degeneration of some tissues in older age, and could assist health management in countries,...


Word of the Day
abrosia
  • Wasting away as a result of abstinence from food.
The word 'abrosia' comes from a Greek roots meaning 'not' and 'eating'.