Latest DNA replication Stories

This discovery holds the potential to reduce healthcare costs for many common inflammatory diseases such as cancer and diabetesSingapore, Nov 21, 2012 - (ACN Newswire) - A*STAR scientists have identified the enzyme, telomerase, as a cause of chronic inflammation in human cancers. Chronic inflammation is now recognized as a key underlying cause for the development of many human cancers, autoimmune disorders, neurodegenerative diseases, and metabolic diseases such as...

Certain mutated cells keep trying to replicate their DNA — with disastrous results — even after medications rob them of the raw materials to do so, according to new research from USC. New imaging techniques allowed scientists to see for the first time that while chemotherapy drugs shut down the DNA replication process of most cancer cells, so-called "checkpoint mutants" just keep chugging along, unwinding the DNA and creating damaged DNA strands that can result in the kind of...

BOCA RATON, Fla., Oct. 1, 2012 /PRNewswire/ -- Noel Thomas, Founder of TA Sciences, a New York, NY-based organization dedicated to lengthening the human lifespan, and Dr. Ed Park, an expert in the field of telomerase activators, will appear on The SUZANNE Show this week to discuss an enzyme that may be able to slow the aging process. Their appearance, which is one in a series devoted to natural life extension, airs Wednesday, October 3, at 7 a.m. (ET/PT) on Lifetime Television....

IPSWICH, Mass., Aug. 8, 2012 /PRNewswire/ -- New England Biolabs (NEB) has released a novel DNA polymerase, Q5((TM)) High-Fidelity DNA Polymerase, that provides the highest fidelity amplification currently available, while also offering robust amplification across the broadest range of amplicons, including those that are GC- and AT-rich. (Photo: http://photos.prnewswire.com/prnh/20120808/NE54308 ) (Logo: http://photos.prnewswire.com/prnh/20090921/NE79207LOGO-b ) High fidelity...

American Heart Association meeting report: BCVS-12 Abstract 62 Damaged and aged heart tissue of older heart failure patients was rejuvenated by stem cells modified by scientists, according to research presented at the American Heart Association's Basic Cardiovascular Sciences 2012 Scientific Sessions. The study is simultaneously published in the Journal of the American College of Cardiology. The research could one day lead to new treatments for heart failure patients, researchers said....

UCLA biochemists have mapped the structure of a key protein–RNA complex that is required for the assembly of telomerase, an enzyme important in both cancer and aging. The researchers found that a region at the end of the p65 protein that includes a flexible tail is responsible for bending telomerase's RNA backbone in order to create a scaffold for the assembly of other protein building blocks. Understanding this protein, which is found in a type of single-celled organism that lives in...

The foundation of biological inheritance is DNA replication This is a coordinated process in which DNA is copied at hundreds of thousands of different sites across the genome at the same time. If the copying mechanism doesn't work properly, the result may be cells with missing or extra genetic material, a hallmark of the genomic instability seen in most birth defects and cancers. Scientists at the University of North Carolina School of Medicine have discovered a protein known as Cdt1....

Researchers at the RIKEN SPring-8 Center in Harima, Japan have clarified for the first time how chromatin in archaea, one of the three evolutionary branches of organisms in nature, binds to DNA. The results offer valuable clues into the evolution of chromatin structure in multi-cellular organisms and promise insights into how abnormalities in such structure can contribute to cancers and gene disorders. Three distinct evolutionary branches of organisms make up all natural forms of life on...

Molecular-level details of mechanism may point to ways to block unwanted cell division Before any cell - healthy or cancerous - can divide, it has to replicate its DNA. So scientists who want to know how normal cells work - and perhaps how to stop abnormal ones - are keen to understand this process. As a step toward that goal, scientists at the U.S. Department of Energy's Brookhaven National Laboratory and collaborators have deciphered molecular-level details of the complex choreography by...

MADRID, March 6, 2012 /PRNewswire/ -- Life Length, the world's leading telomere testing and services company, announced that Drs Sandy Chang and Kathleen Collins have joined its Scientific Advisory Board ("SAB"). Stephen J. Matlin, CEO, Life Length, noted, "We are delighted to welcome these world-renowned telomere and telomerase experts to Life Length's SAB. They will help advance our global leadership. Dr Chang is especially well known for pioneering work in...