Latest DNA replication Stories

2013-07-16 10:34:16

Breaks in the double-strands of the DNA helix can spell trouble, destabilizing the genome and resulting in changes that drive cancer, antibiotic resistance and, on a more positive note, evolution. Scientists can generate these breaks by a variety of extraneous methods in the laboratory, but Baylor College of Medicine scientists Dr. Philip Hastings and Dr. Susan Rosenberg wondered how such breaks occur without outside help - and how they occur in resting cells not actively making new copies...

New Details Of Biochemical Interactions Necessary For Cell Division Identified
2013-07-15 12:05:33

DOE/Brookhaven National Laboratory Building on earlier work exploring the complex choreography by which intricate cellular proteins interact with and copy DNA prior to cell division, scientists at the U.S. Department of Energy's Brookhaven National Laboratory and collaborators have captured a key step-molecular images showing how the enzyme that unwinds the DNA double helix gets drawn to and wrapped around its target. Details of the research, published in the journal Nature Structural...

2013-04-25 20:16:17

A study led by Oscar Fernandez-Capetillo has deciphered the components of the machinery that duplicates DNA, the replisome, on which most chemotherapeutic agents currently act The Genomic Instability Group led by researcher Óscar Fernández-Capetillo at the Spanish National Cancer Research Centre (CNIO), has for the first time obtained a panoramic photo of the proteins that take part in human DNA division, a process known as replication. The research article,...

2013-04-19 17:55:22

Scientists have revealed how a bacterial enzyme has evolved an energy-efficient method to move long distances along DNA. The findings, published in Science, present further insight into the coupling of chemical and mechanical energy by a class of enzymes called helicases, a widely-distributed group of proteins, which in human cells are implicated in some cancers. The new helicase mechanism discovered in this study, led by researchers from the University of Bristol and the Technische...

2013-04-12 15:57:27

Like finally seeing all the gears of a watch and how they work together, researchers from UCLA and UC Berkeley have, for the first time ever, solved the puzzle of how the various components of an entire telomerase enzyme complex fit together and function in a three-dimensional structure. The creation of the first complete visual map of the telomerase enzyme, which is known to play a significant role in aging and most cancers, represents a breakthrough that could open up a host of new...

Fluorescent Tags Help Scientists Solve Mystery Of Human DNA Replication
2013-04-02 05:24:54

redOrbit Staff & Wire Reports - Your Universe Online Scientists at Penn State University have discovered how a vital step in the human DNA replication process — the loading of molecular structures known as sliding clamps onto DNA molecules — is performed. The researchers say their work, the results of which were published in Tuesday´s edition of the journal eLife, will help uncover some of the mystery surrounding this crucial part of the chemical replication...

2013-02-25 10:43:41

Protein uses multiple means to help cells cope when oxygen runs low A protein known for turning on genes to help cells survive low-oxygen conditions also slows down the copying of new DNA strands, thus shutting down the growth of new cells, Johns Hopkins researchers report. Their discovery has wide-ranging implications, they say, given the importance of this copying – known as DNA replication – and new cell growth to many of the body's functions and in such diseases as cancer....

2013-02-17 23:00:56

The TA-65 Users Survey included the collection of qualitative data gathered through survey research. This study outlined the TA-65 longevity and health benefits seen in actual human subjects, during the course of the 6 months. New York, NY (PRWEB) February 17, 2013 Telomeres are protective pieces of DNA material at the ends of every chromosome in every cell in the body. Telomeres, like protective caps at the end of our shoelaces, function to protect the integrity of the genome and preserve...

Word of the Day
  • A Roman unit of weight, 1⁄1728 of a pound.
  • A weight of four grains used in weighing gold and precious stones; a carat.
  • In anatomy, a formation suggesting a husk or pod.
  • The lowest unit in the Roman coinage, the twenty-fourth part of a solidus.
  • A coin of base silver of the Gothic and Lombard kings of Italy.
'Siliqua' comes from a Latin word meaning 'a pod.'