Latest DNA replication Stories
The biological information that makes us unique is encoded in our DNA.
Breaks in the double-strands of the DNA helix can spell trouble, destabilizing the genome and resulting in changes that drive cancer, antibiotic resistance and, on a more positive note, evolution.
Building on earlier work exploring the complex choreography by which intricate cellular proteins interact with and copy DNA prior to cell division, scientists at the U.S. Department of Energy's Brookhaven National Laboratory and collaborators have captured a key step-molecular images showing how the enzyme that unwinds the DNA double helix gets drawn to and wrapped around its target.
The Genomic Instability Group led by researcher Óscar Fernández-Capetillo at the Spanish National Cancer Research Centre (CNIO), has for the first time obtained a panoramic photo of the proteins that take part in human DNA division, a process known as replication.
Scientists have revealed how a bacterial enzyme has evolved an energy-efficient method to move long distances along DNA.
Like finally seeing all the gears of a watch and how they work together, researchers from UCLA and UC Berkeley have, for the first time ever, solved the puzzle of how the various components of an entire telomerase enzyme complex fit together and function in a three-dimensional structure.
Scientists at Penn State University have discovered how a vital step in the human DNA replication process – the loading of molecular structures known as sliding clamps onto DNA molecules – is performed.
A protein known for turning on genes to help cells survive low-oxygen conditions also slows down the copying of new DNA strands, thus shutting down the growth of new cells.
- To swell, as grain or wood with water.