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Latest DNA replication Stories

2012-12-28 15:41:56

One approach to understanding components in living organisms is to attempt to create them artificially, using principles of chemistry, engineering and genetics. A suite of powerful techniques–collectively referred to as synthetic biology–have been used to produce self-replicating molecules, artificial pathways in living systems and organisms bearing synthetic genomes. In a new twist, John Chaput, a researcher at Arizona State University´s Biodesign Institute and colleagues...

2012-12-12 23:08:52

Cell aging, or cellular senescence, has an important role in the natural physiological response to tumor development. Activated oncogenes are able to induce senescence, and recent findings have suggested that oncogene-induced senescence (OIS) could play a key role in future cancer therapy. Researchers have now identified a previously unknown mechanism in the regulation of OIS. This study is published online in advance of the January issue of The American Journal of Pathology. In many types...

2012-11-21 06:20:29

This discovery holds the potential to reduce healthcare costs for many common inflammatory diseases such as cancer and diabetesSingapore, Nov 21, 2012 - (ACN Newswire) - A*STAR scientists have identified the enzyme, telomerase, as a cause of chronic inflammation in human cancers. Chronic inflammation is now recognized as a key underlying cause for the development of many human cancers, autoimmune disorders, neurodegenerative diseases, and metabolic diseases such as diabetes. This enzyme,...

2012-11-20 11:47:58

Certain mutated cells keep trying to replicate their DNA – with disastrous results – even after medications rob them of the raw materials to do so, according to new research from USC. New imaging techniques allowed scientists to see for the first time that while chemotherapy drugs shut down the DNA replication process of most cancer cells, so-called "checkpoint mutants" just keep chugging along, unwinding the DNA and creating damaged DNA strands that can result in the kind of...

2012-07-24 10:14:13

American Heart Association meeting report: BCVS-12 Abstract 62 Damaged and aged heart tissue of older heart failure patients was rejuvenated by stem cells modified by scientists, according to research presented at the American Heart Association's Basic Cardiovascular Sciences 2012 Scientific Sessions. The study is simultaneously published in the Journal of the American College of Cardiology. The research could one day lead to new treatments for heart failure patients, researchers said....

2012-06-19 14:03:05

UCLA biochemists have mapped the structure of a key protein—RNA complex that is required for the assembly of telomerase, an enzyme important in both cancer and aging. The researchers found that a region at the end of the p65 protein that includes a flexible tail is responsible for bending telomerase's RNA backbone in order to create a scaffold for the assembly of other protein building blocks. Understanding this protein, which is found in a type of single-celled organism that lives...

DNA Replication Protein Plays Role In Cancer
2012-05-14 08:46:39

The foundation of biological inheritance is DNA replication This is a coordinated process in which DNA is copied at hundreds of thousands of different sites across the genome at the same time. If the copying mechanism doesn't work properly, the result may be cells with missing or extra genetic material, a hallmark of the genomic instability seen in most birth defects and cancers. Scientists at the University of North Carolina School of Medicine have discovered a protein known as Cdt1....


Word of the Day
monteith
  • A large punch-bowl of the eighteenth century, usually of silver and with a movable rim, and decorated with flutings and a scalloped edge. It was also used for cooling and carrying wine-glasses.
  • A kind of cotton handkerchief having white spots on a colored ground, the spots being produced by a chemical which discharges the color.
This word is possibly named after Monteith (Monteigh), 'an eccentric 17th-century Scotsman who wore a cloak scalloped at the hem.'
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