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Latest DNA vaccination Stories

2010-06-09 12:57:58

An inexpensive system for earlier disease diagnosis could save innumerable lives. It would also have a profound impact on the nation's healthcare industry, currently buckling under the strain of spiraling costs. Now Dr. Bart Legutki, a researcher at the Biodesign Institute at Arizona State University has pioneered a method for profiling the immune system, using clues provided by antibody activity to track an individual's state of health.  The work was done in collaboration with Dr....

2010-05-24 13:44:36

Researchers at Mount Sinai School of Medicine for the first time have determined that bone marrow cells play a critical role in fighting respiratory viruses, making the bone marrow a potential therapeutic target, especially in people with compromised immune systems. They have found that during infections of the respiratory tract, cells produced by the bone marrow are instructed by proteins to migrate to the lungs to help fight infection. The data are published in the current issue of Cell...

2010-05-24 11:00:29

A DNA-vaccine that restricts the supply of blood to tumors has been developed by scientists at the Karolinska Institutet. The vaccine slows the growth of breast cancer tumors in mice. If a cancer tumor is to become larger than a few millimeters it must be able to stimulate the formation of new blood vessels, in order to secure the supply of oxygen and nutrients. Drugs that prevent the growth of blood vessels are thus a potential treatment alternative for tumors. A protein known as ...

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2010-05-21 09:13:52

New research has found that an experimental Ebola vaccine developed by researchers at the National Institutes of Health protects monkeys against not only the two most lethal Ebola virus species for which it was originally designed, both recognized in 1976, but also against a newer Ebola virus species that was identified in 2007. Nancy J. Sullivan, Ph.D., of the Vaccine Research Center at the National Institute of Allergy and Infectious Diseases (NIAID), NIH, led the study team, which included...

2010-04-19 13:38:56

Laboratory research and clinical studies are beginning to demonstrate that DNA vaccines can be as effective as traditional vaccines, reports Genetic Engineering & Biotechnology News (GEN). A number of factors are driving the growth of the field, especially new approaches to electroporation, vaccine formulation, and vector design, according to the April 15 issue of GEN (http://www.genengnews.com/articles/chitem.aspx?aid=3247). "A lot of development is focused on the creation of DNA...

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2010-03-03 12:52:16

Mosaic vaccines show promise in reducing the spread of deadly virus Two teams of researchers"”including Los Alamos National Laboratory theoretical biologists Bette Korber, Will Fischer, Sydeaka Watson, and James Szinger"”have announced an HIV vaccination strategy that has been shown to expand the breadth and depth of immune responses in rhesus monkeys. Rhesus monkeys provide the best animal model currently available for testing HIV vaccines. The research appeared in two...

2010-03-02 12:37:04

Researchers from HZI vaccine department examine new adjuvant to improve vaccinations The adjuvants present in vaccines have a bad reputation. For most people, they are only unnecessary compounds within a medicinal product. This is a misunderstanding since adjuvants have a critical impact on the success of a vaccination. In the best case scenario, one single vaccination shot would be now sufficient for conferring life-long protection. Vaccines are one of the most powerful tools against...

2010-01-27 16:43:04

Blocking key protein in mice helps them resist viral infection LA JOLLA, CA -- Researchers at The Scripps Research Institute have discovered a potential new way to stimulate the immune system to prevent or clear a viral infection. By blocking the action of a key protein in the mouse immune system, they were able to boost immune "memory" in those mice"”work that may one day help doctors increase the effectiveness of human vaccines designed to prevent viral infections. Immune memory in...

2010-01-19 21:14:59

Research published this week in PLoS Medicine synthesizes information from many different studies that attempt to link specific antibody responses to Plasmodium falciparum with protection from clinical malaria and comes to important conclusions about which antigens might be worth advancing as vaccine candidates. Malaria is a major global health problem. P. falciparum is the major cause and kills about one million people every year, mainly young children. However, immune responses to malaria...

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2009-12-15 15:40:00

Mizzou scientists point to an imbalance of white blood cells in newborns As soon as babies are born, they are susceptible to diseases and infections, such as jaundice and e-coli. For up to a month, their immune systems aren't adequately developed to fight diseases. Although these infections are often minor, they can lead to serious problems if left untreated. To help strengthen newborns' immune systems, University of Missouri researchers have pinpointed a group of depleted white blood cells,...


Word of the Day
mallemaroking
  • Nautical, the visiting and carousing of sailors in the Greenland ships.
This word is apparently from a confusion of two similar Dutch words: 'mallemerok,' a foolish woman, and 'mallemok,' a name for some persons among the crew of a whaling vessel.