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Latest DNA vaccination Stories

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2009-07-28 09:15:00

Schistosomiasis, one of the most important of the neglected tropical diseases, is caused by infection with parasitic helminths of the genus Schistosoma. These parasites are long lived (>10 years) and dwell within blood vessels, where they produce eggs that become the focus of intense, chronic inflammatory responses. In severe cases, this inflammation is associated with life-threatening liver disease.No vaccine is currently available to prevent schistosomiasis. Options for treating the...

2009-07-21 14:50:42

A new DNA vaccine inhibited malignant melanoma, a deadly form of skin cancer, in mice by eliciting antibodies that target a gastrin-releasing peptide which is known to play a key role in cancer development. The researchers from China and the U.S. report their findings in the July 2009 issue of the journal Clinical and Vaccine Immunology.Gastrin-releasing peptide (GRP) is an important human peptide that regulates gastric acid secretion and motor function as well as elicits gastrin release....

2009-06-29 08:50:00

Swedish researchers have discovered that babies born by Caesarean section experience changes to the DNA pool in their white blood cells, which could be connected to altered stress levels during this method of delivery, according to the July issue of Acta Paediatrica.  It is thought that these genetic changes, which differ from normal vaginal deliveries, could explain why people delivered by C-section are more susceptible to immunological diseases such as diabetes and asthma in later...

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2009-06-26 14:20:00

New research suggests that a common immunosuppressive drug may have the ability to boost the power of vaccines, BBC News reported. The drug rapamycin is commonly given to transplant patients to stop their bodies rejecting donor organs, but scientists at Emory University discovered during tests on mice and monkeys that it enhanced the response of their immune system to experimental vaccines. The study also raises hopes of a new generation of potent vaccines. According to the research published...

2009-06-11 10:21:25

 DNA vaccination using lupus autoantigens and interleukin-10 (IL-10, a cytokine that plays an important role in regulating the immune system) has potential as a novel therapy to induce antigen specific tolerance and may help to prevent kidney damage in patients with systemic lupus erythematosus (SLE), according to a new study presented today at EULAR 2009, the Annual Congress of the European League Against Rheumatism in Copenhagen, Denmark.SLE is a complex, chronic autoimmune disease...

2009-06-01 23:56:44

U.S. army scientists say one of the newest DNA vaccine delivery methods relies on technology known as the gene gun, which is less painful then needles. Connie Schmaljohn, senior research scientist at the U.S. Army Medical Research Institute of Infectious Diseases, told Armed with Science: Research and Applications for the Modern Military listeners during an audio Web cast that DNA offers a number of advantages over conventional vaccine approaches, especially with regard to biodefense...

2009-05-26 05:00:00

HALIFAX, NS, May 26 /PRNewswire/ - ImmunoVaccine Technologies Inc. (IVT), a Canadian vaccine development company, announced a research partnership with FIT Biotech, a Finland-based, clinical stage company that develops DNA vaccines. This research will formulate FIT Biotech's GTU(R) MultiHIV DNA plasmid with IVT's DepoVax(TM) vaccine delivery system to advance a therapeutic HIV vaccine. "DepoVax(TM) will act as a vector to deliver FIT Biotech's GTU(R) MultiHIV DNA vaccine and our goal is to...

2009-04-28 08:37:00

Peptide-based vaccines could prove efficacious for both prophylactic and therapeutic treatments VIENNA, Va., April 28 /PRNewswire-FirstCall/ -- CEL-SCI Corporation (NYSE AMEX: CVM) announced today that preclinical studies have demonstrated that vaccines utilizing its proprietary L.E.A.P.S.(TM) (Ligand Epitope Antigen Presentation System) vaccine technology could potentially induce protection against illnesses such as swine influenza. In pre-clinical studies using mouse models, several...

2009-04-28 10:13:16

New delivery method could result in simpler, safer, painless vaccines Flu vaccine delivered through skin patches containing microneedles has proven just as effective at preventing influenza in mice as intramuscular, hypodermic flu immunization. A team of researchers at Emory University and the Georgia Institute of Technology believes the new microneedle skin patch method of delivering flu vaccine could improve overall seasonal vaccination coverage in people because of decreased pain,...

2009-03-04 14:33:35

Australian scientists say a bird flu vaccine is closer to reality thanks to their finding that boosting T-cell immunity can protect humans from the disease. The 'Killer T cell' is the hit-man of the immune system, said University of Melbourne Professor Stephen Turner, lead author of the research. It is able to locate and destroy virus-infected cells in our body helping rid us of infection. Unfortunately, current influenza vaccines are poor at inducing killer T cell immunity. Therefore, we...