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Latest Dopamine agonists Stories

2011-05-11 19:32:02

Scientists are reporting development of three promising formulations that could be used in a vaccine to treat methamphetamine addiction "” one of the most serious drug abuse problems in the U.S. The report appears in the Journal of the American Chemical Society. In the paper, Kim Janda and colleagues note that methamphetamine use and addiction cost the U.S. more than $23 billion annually due to medical and law enforcement expenses, as well as lost productivity. The drug, also called...

2011-04-14 06:00:00

BRUSSELS, April 14, 2011 /PRNewswire/ -- New 5-year data from the longest prospective open-label Restless Legs Syndrome (RLS) study to date, show that Neupro® (rotigotine) demonstrated continued symptomatic clinical benefit with a low risk of augmentation. Over the five year period, clinically significant augmentation occurred in 5.1% of patients receiving rotigotine at EU approved doses (1, 2 and 3 mg/24h) and in 13.2% of patients receiving one of the five evaluated...

2011-04-13 12:30:00

BRUSSELS, April 13, 2011 /PRNewswire/ -- New rotigotine data shown in four poster presentations at the 63rd Annual Meeting of the American Academy of Neurology (AAN) in Hawaii, U.S., highlighted the importance in Parkinson's disease (PD) of addressing both motor- and non-motor symptoms, such as sleep. The data also demonstrated the long-term efficacy and tolerability of rotigotine and showed that plasma rotigotine levels remained stable following patch removal and application of a new...

2011-04-13 07:42:03

(Ivanhoe Newswire) -- Results of the first, long-term clinical trial show the investigational drug safinamide may reduce dyskinesia (involuntary movements) in mid-to-late stage Parkinson's disease. "Our findings over a two-year treatment period suggest that taking safinamide in addition to levodopa and other dopaminergic treatments could help patients who continue to experience tremors and involuntary movement problems," study author Ravi Anand, M.D., a consultant with Newron Pharmaceuticals...

2011-04-08 15:46:05

A study of the salamander brain has led researchers at Karolinska Institutet to discover a hitherto unknown function of the neurotransmitter dopamine. In an article published in the prestigious scientific journal Cell Stem Cell they show how in acting as a kind of switch for stem cells, dopamine controls the formation of new neurons in the adult brain. Their findings may one day contribute to new treatments for neurodegenerative diseases, such as Parkinson's. The study was conducted using...

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2011-03-21 06:20:00

Despite Minnesota lawmakers seeking a ban on chemicals used in common synthetic drugs, revelers at a spring break party in a Minneapolis suburb overdosed this week on one of the risky substances, leaving one dead, officials told Reuters on Sunday. Iowa Rep. Sen. Charles Grassley, just two days ago proposed a similar ban on chemicals used in such synthetic drugs known as Spice and K2, a synthetic marijuana. Trevor Robinson, 19, died of an overdose at the spring break party while ten other...

2011-03-09 12:59:00

NESS ZIONA, Israel, March 9, 2011 /PRNewswire/ -- NeuroDerm, Ltd. announced today the enrollment of the first group of patients in its Phase I/II clinical trial of ND0611, a new patch for the treatment of Parkinson's disease. ND0611, a proprietary carbidopa liquid formula administered via a dermal patch, is designed to increase the bioavailability and efficacy of orally- administered levodopa and thus improve treatment of Parkinson's disease. In pre-clinical studies, plasma...

2010-12-07 12:56:01

A drug prescribed for Parkinson's disease may also treat restless leg syndrome without the adverse side effects of current therapies, Medical College of Georgia researchers say. Rasagaline works by prolonging the effect of dopamine, a chemical that transmits signals between nerve cells in the brain. The cause of RLS is unknown, but research suggests a dopamine imbalance. Parkinson's is caused by a dopamine insufficiency. "The hope is that Rasagaline, because it prolongs the effect of existing...

2010-11-30 07:00:00

BURLINGTON, Mass., Nov. 30, 2010 /PRNewswire/ -- Decision Resources, one of the world's leading research and advisory firms for pharmaceutical and healthcare issues, finds that, when comparing dopamine agonist use for Parkinson's disease, more frequent use of once-daily formulations of Requip (GlaxoSmithKline's Requip, Requip XL/LP/Modutab/RP/Prolib) and Mirapex (Boehringer Ingelheim's Mirapex/Sifrol/Mirapexin; Mirapex ER/Mirapexin ER/Sifrol Retard) occurs in France than in the remaining...

2010-10-21 13:06:25

Researchers at the University of Copenhagen have succeeded in creating a model of the way the brain releases dopamine, an important chemical involved in transmitting signals between nerve cells. The model, the product of an interdisciplinary collaboration, will be an important tool in helping scientists understand how we learn and how the brain perceives reward and punishment. It is hoped that the model can be used to understand drug addiction and in the treatment of schizophrenia. In the...


Word of the Day
barghest
  • A goblin in English folklore, often appearing in the shape of a large dog and believed to portend imminent death or misfortune.
  • A ghost, wraith, hobgoblin, elf, or spirit.
The origin of 'barghest' is not known, but it may be from perhaps burh-ghest, town-ghost, or German Berg-geist (mountain spirit) or Bär-geist (bear-spirit).
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