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2012-10-23 15:24:32

RESEARCH TRIANGLE PARK, N.C., Oct. 23, 2012 /PRNewswire-USNewswire/ -- Aaron Williams, former vice president of international business development at RTI International and, most recently, Director of the U.S. Peace Corps, will return to RTI as executive vice president of the International Development Group starting Monday, Oct. 29. "Aaron Williams is the ideal person to lead our global development programs as we go forward," said RTI President and CEO Wayne Holden. "He knows our...

Kicking Cocaine Addiction With A One-Two Punch
2012-08-09 10:56:41

Connie K. Ho for redOrbit.com — Your Universe Online Researchers from Scripps Research Institute recently revealed that a two-drug combination could possibly help those battling cocaine addiction. The combination made up of naltrexone and buprenoprine, two existing pharmaceutical drugs, is a therapy that would help reduce individuals´ want for cocaine and also lessen their feelings of withdrawal. Scientists believed that the therapy is a step forward as there are currently no...

2012-07-30 06:27:03

(Ivanhoe Newswire) — Cocaine is presently the most abused major stimulant drug in America. It has also become the drug most frequently involved in emergency department visits. Now researchers are saying the solution to the addiction problem could be in the form of enzymes. Researchers from the University of Kentucky have designed and discovered a series of highly efficient enzymes that effectively metabolize cocaine. These high-activity cocaine-metabolizing enzymes could potentially...

2012-07-27 10:59:49

Researchers from the University of Kentucky have designed and discovered a series of highly efficient enzymes that effectively metabolize cocaine. These high-activity cocaine-metabolizing enzymes could potentially prevent cocaine from producing physiological effects, and could aid in the treatment of drug dependency. The results of this study by Chang-Guo Zhan et al are published in the journal PLOS Computational Biology. The effectiveness of the enzymes' work was evaluated through...

2012-06-25 10:55:40

Researchers at Yale School of Medicine have zeroed in on a set of neurons in the part of the brain that controls hunger, and found that these neurons are not only associated with overeating, but also linked to non-food associated behaviors, like novelty-seeking and drug addiction. Published in the June 24 online issue of Nature Neuroscience, the study was led by Marcelo O. Dietrich, postdoctoral associate, and Tamas L. Horvath, the Jean and David W. Wallace Professor of Biomedical Research...

2012-06-11 21:25:24

PET imaging studies reveal how an inoculation against cocaine addiction uses the body's own immune system to prevent a high Addicts unable to kick a cocaine habit could one day be vaccinated against cocaine and see proof with a molecular imaging technique that shows how the vaccine prompts antibodies to whisk away the drug before it can reach the brain, say researchers at SNM's 59th Annual Meeting. "Vaccination offers a whole new treatment paradigm for drug addiction," says Shankar...

Chronic Cocaine Use Triggers Changes In Brain's Neuron Structure
2012-05-09 14:26:44

Chronic exposure to cocaine reduces the expression of a protein known to regulate brain plasticity, according to new, in vivo research on the molecular basis of cocaine addiction. That reduction drives structural changes in the brain, which produce greater sensitivity to the rewarding effects of cocaine. The finding suggests a potential new target for development of a treatment for cocaine addiction. It was published last month in Nature Neuroscience by researchers at the University at...

2012-05-03 05:22:46

(Ivanhoe Newswire)-- The United Nations Office on Drugs and Crime estimates that cocaine is used by up to 21 million individuals worldwide, with approximately 1 per cent of these individuals becoming dependent. Now, a new study shows that frequent cocaine abuse can lead to accelerated aging of the brain. Cocaine is a strong central nervous system stimulant that increases levels of dopamine, a brain chemical associated with pleasure and movement, in the brain´s reward circuit. The...

2012-04-24 22:18:34

Research shows chronic users' brains age dramatically faster than their non-drug-using peers New research by scientists at the University of Cambridge suggests that chronic cocaine abuse accelerates the process of brain aging. The study, published today 25 April in Molecular Psychiatry, found that age-related loss of grey matter in the brain is greater in people who are dependent on cocaine than in the healthy population. For the study, the researchers scanned the brains of 120 people...

2012-04-23 11:18:35

New research from Mount Sinai Medical Center in New York reveals that repeated exposure to cocaine decreases the activity of a protein necessary for normal functioning of the brain's reward system, thus enhancing the reward for cocaine use, which leads to addiction. Investigators were also able to block the ability of repeated cocaine exposure, to induce addiction. The findings, published online April 22 in the journal Nature Neuroscience, provide the first evidence of how cocaine changes the...