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Latest Dopamine reuptake inhibitors Stories

2012-02-22 11:03:02

When first exposed to cocaine, the adolescent brain launches a strong defensive reaction designed to minimize the drug's effects, Yale and other scientists have found. Now two new studies by a Yale team identify key genes that regulate this response and show that interfering with this reaction dramatically increases a mouse's sensitivity to cocaine. The findings may help explain why risk of drug abuse and addiction increase so dramatically when cocaine use begins during teenage years....

2012-01-30 14:09:15

When it comes to addiction, sex matters. A new brain imaging study by Yale School of Medicine researchers suggests stress robustly activates areas of the brain associated with craving in cocaine-dependent women, while drug cues activate similar brain regions in cocaine-dependent men. The study, expected to be published online Jan. 31 in the American Journal of Psychiatry, suggests men and women with cocaine dependence might benefit more from different treatment options. "There are...

2012-01-11 15:30:17

Research published by Cell Press in the January 12 issue of the journal Neuron provides fascinating insight into a newly discovered brain mechanism that limits the rewarding impact of cocaine. The study describes protective delayed mechanism that turns off the genes that support the development of addiction-related behaviors. The findings may lead to a better understanding of vulnerability to addiction and as well as new strategies for treatment. Drug addiction is associated with...

2011-11-04 10:37:15

Cigarettes and alcohol serve as gateway drugs, which people use before progressing to the use of marijuana and then to cocaine and other illicit substances; this progression is called the "gateway sequence" of drug use. An article in Science Translational Medicine by Amir Levine, MD, Denise Kandel, PhD; Eric Kandel, MD; and colleagues at Columbia University Medical Center provides the first molecular explanation for the gateway sequence. They show that nicotine causes specific changes in the...

2011-08-11 21:29:23

When a research team asked cocaine addicts to choose, hypothetically, between money now or cocaine of greater value later, "preference was almost exclusively for the money now," said Warren K., Bickel, professor in the Virginia Tech Carilion Research Institute, director of the Advanced Recovery Research Center, and professor of psychology in the College of Science at Virginia Tech. This result is significantly different from previous studies where a subject chooses between some money now or...

2011-07-27 18:43:11

While some pain killers need to be injected into the damaged tissue in order to work, topical anaesthetics only need to be spread on the surface. The earliest examples of "topical" anaesthetics contained cocaine, but now a new systematic review has shown that newer agents that don't contain cocaine can effectively treat pain caused by torn skin. This makes these pain killers an attractive choice for doctors who need to sew-up a patient's skin wound. This finding was reached after a team of...

2011-07-18 12:20:00

JERUSALEM, July 18, 2011 /PRNewswire/ -- IDenta Corp. (PINKSHEETS: IDTA) CEO Yaacov Shoham today announced additional details of the agreement with Expobrax Export & Import Ltd. Mr. Shoham stated, "I want to give a broader picture regarding the agreement signed between IDenta Corp. and the Brazilian company, Expobrax Export & Import Ltd. www.expobrax.com.Br IDenta Corp. had revealed the connection with the Brazilian company in the press release from June 7, 2011. The owner of...

2011-07-15 15:16:21

A common medication shown to hinder retrieval of memories associated with cocaine use in animal models New discoveries by researchers at the University of Wisconsin-Milwaukee (UWM) offer potential for development of a first-ever pharmacological treatment for cocaine addiction. A common beta blocker, propranolol, currently used to treat people with hypertension and anxiety, has shown to be effective in preventing the brain from retrieving memories associated with cocaine use in...

2011-07-14 15:46:53

Even after accounting for current crack use, a new study finds that women in drug court who are experiencing current major depression are more likely to use crack within four months than other women in drug court. The paper's lead author argues that depression screening and treatment may be important components of drug court services for crack-using women. Women who are clinically depressed at the time they enter drug court have a substantially higher risk of using crack cocaine within four...


Word of the Day
abrosia
  • Wasting away as a result of abstinence from food.
The word 'abrosia' comes from a Greek roots meaning 'not' and 'eating'.