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Latest Dopamine reuptake inhibitors Stories

2011-01-04 14:23:50

Novel vaccine is poised to move quickly into human trials Researchers have produced a lasting anti-cocaine immunity in mice by giving them a safe vaccine that combines bits of the common cold virus with a particle that mimics cocaine. In their study, published Jan. 4 in the online edition of Molecular Therapy and funded by the National Institute on Drug Abuse, the researchers say this novel strategy might be the first to offer cocaine addicts a fairly simple way to break and reverse their...

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2010-11-18 10:15:00

For the first time, a therapeutic treatment has been shown to block the retrieval of memories associated with drug addiction Two separate discoveries by researchers at the University of Wisconsin-Milwaukee (UWM) offer potential for development of a first-ever pharmacological treatment for cocaine addiction. In one study, a common beta blocker, propranolol, currently used to treat hypertension and anxiety, has shown to be effective in preventing the brain from retrieving memories associated...

2010-11-16 19:06:37

Teen brain responds differently to drugs than adult New research released today shows teenagers respond differently to drugs than adults and explores the long-lasting effects of drug use on brain development. One study shows people who start using drugs at a young age have greater cognitive shortfalls, including mental flexibility. Animal studies also suggest adolescents are more susceptible to lower doses of cocaine, are willing to work more for a cocaine "fix" than adults, and are at risk...

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2010-11-01 08:05:00

When both the effects on the individual and the impact on society as whole is taken into account, alcohol is more dangerous than heroin or crack cocaine, claims a new study published in UK scientific journal The Lancet. In their report, former British government drug advisor David Nutt and researchers with the Independent Scientific Committee on Drugs (ISCD) tested 20 drugs using 16 different measures of harm caused both to the individual taking the substance as well as to wider society....

2010-10-26 06:30:00

QUEBEC CITY, Oct. 26 /PRNewswire/ - Aeterna Zentaris Inc. (NASDAQ: AEZS, TSX: AEZ), today announced that it will make a poster presentation, as well as an oral presentation on preclinical results for AEZS-131, a leading highly selective Erk inhibitor, which support its further evaluation as a potential anticancer compound in monotherapy or in combination with PI3K/Akt pathway inhibitors. Both presentations will be made during the Cambridge Healthtech Institute's 8(th)...

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2010-08-23 12:20:00

Researchers at Gilead Sciences Inc. said on Sunday that an extract of the kudzu vine being developed to treat alcoholism may also help treat cocaine addiction. The Gilead team reported in the journal Nature Medicine that tests on rats showed the drug could stop them from giving themselves cocaine. Gilead inherited the experimental drug a year ago after it acquired CV Therapeutics Inc.  A spokesman for the company said it was working to try to bring the drug to the market. "There is no...

2010-08-16 14:25:09

Findings represent additional clues to help predict vulnerability to drug abuse A regulatory protein best known for its role in a rare genetic brain disorder also may play a critical role in cocaine addiction, according to a recent study in rats, funded by the National Institute on Drug Abuse (NIDA), a component of the National Institutes of Health. The study was published today in the journal Nature Neuroscience. Researchers at the Scripps Research Institute in Jupiter, Fla. found that...

2010-08-10 15:44:11

The authors of a new study in Biological Psychiatry explore pharmacological strategies for reducing cocaine self-administration in animals that may have implications for treating cocaine dependence in humans. Glutamate is the primary excitatory neurotransmitter in the brain, which has been implicated in drug addiction. Metabotropic glutamate receptors (mGluRs) represent a family of G-protein coupled receptors that modulate glutamate transmission. Glutamate is an important neurotransmitter...

2010-07-09 13:48:04

Discovery could lead to better ways of predicting drug abuse risk and treating addictions A specific and remarkably small fragment of RNA appears to protect rats against cocaine addiction - and may also protect humans, according to a recent study funded by the National Institute on Drug Abuse (NIDA), a component of the National Institutes of Health. The study was published today in the journal Nature. RNA (ribonucleic acid) molecules are known to play critical roles in the translation of...

2010-06-02 20:24:39

Further research is needed Cancer-related fatigue is often a major problem for cancer patients, beginning at diagnosis, during treatment and after completing therapy. Researchers at Mayo Clinic (http://www.mayoclinic.org/oncology-rst/) and the North Central Cancer Treatment Group (http://ncctg.mayo.edu/) (NCCTG) recently completed a study testing methylphenidate in the treatment of cancer-related fatigue and found that, while it did not improve fatigue for a broad group of patients, the data...


Word of the Day
omphalos
  • The navel or umbilicus.
  • In Greek archaeology: A central boss, as on a shield, a bowl, etc.
  • A sacred stone in the temple of Apollo at Delphi, believed by the Greeks to mark the 'navel' or exact center-point of the earth.
'Omphalos' comes from the ancient Greek.
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