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Last updated on April 19, 2014 at 7:50 EDT

Latest Douglas A. Melton Stories

More Effective Diabetes Treatment From Betatrophin Hormone
2013-04-26 04:57:18

redOrbit Staff & Wire Reports - Your Universe Online A hormone known as betatrophin could be the key to new, more effective treatments for type 2 diabetes, researchers from the Harvard Stem Cell Institute (HSCI) have discovered. Writing in the journal Cell, HSCI co-director Doug Melton and postdoctoral fellow Peng Yi report betatrophin causes the production rate of insulin-secreting pancreatic beta cells to increase by as much as 30 times normal levels. According to the study,...

2012-04-18 21:18:23

Stem cell and regenerative medicine expert Dr. Malgorzata Borowiak has been named Baylor College of Medicine's fifth McNair Scholar. She will focus on diabetes. Using stem cell technology, Borowiak's research focuses on understanding the mechanisms of type 1 diabetes to identify new, cellular treatments for the disease. The McNair Scholar program at BCM, supported by the Robert and Janice McNair Foundation and managed by the McNair Medical Institute, identifies outstanding scientists...

2011-07-13 23:25:15

Adult-derived stem cells could pave the way for new treatment of diabetes, says TAU researcher Stem cells from early embryos can be coaxed into becoming a diverse array of specialized cells to revive and repair different areas of the body. Therapies based on these stem cells have long been contemplated for the treatment of diabetes, but have been held back by medical and ethical drawbacks. Now researchers at Tel Aviv University are capitalizing on the "memories" of stem cells generated from...

2010-09-15 07:00:00

SOUTH SAN FRANCISCO, Calif., Sept. 15 /PRNewswire/ -- iPierian, Inc., the leading biopharmaceutical company using patient-derived induced pluripotent stem cells (iPSCs) for drug discovery, today announced that FierceBiotech has named iPierian as one of 2010's Fierce 15, designating it as one of the most promising biotech companies in the industry. Every year FierceBiotech evaluates hundreds of private companies for its annual list, which is based on a variety of factors such as the...

2010-06-15 09:24:00

SOUTH SAN FRANCISCO, Calif., June 15 /PRNewswire/ -- iPierian, Inc., the leading biopharmaceutical company focused on creating new therapeutics using patient-derived induced pluripotent stem cells (iPSCs), today announced that it will present data from its iPSC research programs at the International Society for Stem Cell Research (ISSCR) 8th Annual Meeting, June 16-19, 2010, in San Francisco, CA. Data presented in a poster entitled, Discovery of disease gene expression signature in...

2010-04-29 15:20:00

SOUTH SAN FRANCISCO, Calif., April 29 /PRNewswire/ -- iPierian, Inc., the leading company focused on creating new therapeutics discovered using cellular reprogramming and directed differentiation of patient cells, today announced that it has been awarded a three-year $1.5 million "Basic Biology Award" from the California Institute of Regenerative Medicine (CIRM). The grant will be used to fund the study of mechanisms of cellular reprogramming with the specific aim of enhancing the...

2010-04-15 14:29:34

A new technique for reprogramming human adult cells could greatly improve the safety and efficiency of producing patient-specific stem cells for use in a range of therapeutic applications to repair or replace damaged or diseased tissues. A description of this innovative strategy is published in the peer-reviewed journal Cellular Reprogramming, published by Mary Ann Liebert, Inc. The paper is available free online. Stem cells offer great promise for use in cellular therapy to regenerate...

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2010-02-08 06:35:00

Tiny circles of DNA are the key to a new and easier way to transform stem cells from human fat into induced pluripotent stem cells for use in regenerative medicine, say scientists at the Stanford University School of Medicine. Unlike other commonly used techniques, the method, which is based on standard molecular biology practices, does not use viruses to introduce genes into the cells or permanently alter a cell's genome. It is the first example of reprogramming adult cells to pluripotency...

2010-01-27 16:30:20

STANFORD, Calif. -- Even Superman needed to retire to a phone booth for a quick change. But now scientists at the Stanford University School of Medicine have succeeded in the ultimate switch: transforming mouse skin cells in a laboratory dish directly into functional nerve cells with the application of just three genes. The cells make the change without first becoming a pluripotent type of stem cell -- a step long thought to be required for cells to acquire new identities. The...

2009-09-01 04:00:00

BOSTON, Sept. 1 /PRNewswire/ -- Stemgent, Inc. announced today that it has pledged a financial gift to the Harvard Stem Cell Institute (HSCI) Seminar Series Fund in support of the HSCI 2009 - 2010 Seminar Series. Terms of the gift were not disclosed. The HSCI Seminar Series is an educational program for the stem cell science community in which pioneers in the national and international realm of stem cell research, including many from the Harvard-affiliated senior faculty, present...