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Latest Douglas A. Melton Stories

2009-08-06 08:00:00

SOUTH SAN FRANCISCO, Calif., Aug. 6 /PRNewswire/ -- iPierian, Inc., a biopharmaceutical company focused on changing the paradigm of drug discovery and development through the application of cellular reprogramming, today announced the appointments of Dr. Chad Cowan and Dr. Konrad Hochedlinger to the company's Scientific Advisory Board (SAB). "Drs. Cowan and Hochedlinger are leading scientists in stem cell research and their addition to the iPierian SAB rounds out an exemplary group of...

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2009-07-10 11:55:00

For years researchers have been searching for a way to treat diabetics by reactivating their insulin-producing beta cells, to no avail. Now, they may be one step closer. A protein, whose role in pancreatic development has long been recognized, has been discovered to play an additional and previously unknown regulatory role in the development of cells in the immature endocrine system. These cells ultimately give rise to pancreatic islet cells, which include beta cells.By carefully defining the...

2009-07-08 01:02:00

SOUTH SAN FRANCISCO, Calif. and BOSTON, July 8 /PRNewswire/ -- iZumi Bio, Inc. and Pierian, Inc. today announced they have merged to form a new company, iPierian, Inc. Building on the iZumi infrastructure and vision, the company is focused on the application of cellular reprogramming to change the paradigm of drug discovery. The scientific leadership of the company will accelerate the development of new therapeutics using induced pluripotent stem (iPS) cells for patients with...

2009-01-14 10:00:00

- National Poll Reveals Three-Quarters of Americans Want President-Elect Obama to Deliver on Campaign Commitment to Lift Restrictions on Embryonic Stem Cell Research - WASHINGTON, Jan. 14 /PRNewswire-USNewswire/ -- The Coalition for the Advancement of Medical Research (CAMR) today released a white paper, Catalyst For Cures: Embryonic Stem Cell Research, which outlines the views of nine of the nation's leading scientists on the promises and challenges of embryonic stem cell research. In...

2008-12-31 15:54:27

The successful creation of the first induced pluripotent stem (iPS) cell line from adult monkey skin may have important implications for direct reprogramming capabilities across different species. Previous studies have shown that induction of four key transcription factors can reprogram adult mouse and human skin cells into iPS cells. Until now, iPS cell creation had not been demonstrated in any other species. Researchers at Peking University in Beijing, China retrofit viruses to express the...

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2008-10-13 13:15:00

Researchers said on Sunday they found a shortcut to transforming ordinary skin cells into powerful stem cells by "sprinkling" a chemical onto the cells. The team at the Harvard Stem Cell Institute in Massachusetts added the chemical to use just two genes to transform ordinary human skin cells into more powerful induced pluripotent stem cells or iPS cells. "This study demonstrates there's a possibility that instead of using genes and viruses to reprogram cells, one can use chemicals," said Dr....

2008-08-29 03:00:10

By Malcolm Ritter NEW YORK - Talk about an extreme makeover: Scientists have transformed one type of cell into another in living mice, a big step toward the goal of growing replacement tissues to treat a variety of diseases. The cell identity switch turned ordinary pancreas cells into the rarer type that churns out insulin, essential for preventing diabetes. But its implications go beyond diabetes to a host of possibilities, scientists said. It's the second advance in about a year...

2008-08-29 00:00:11

By The Associated Press NEW YORK (AP) - Talk about an extreme makeover: Scientists have transformed one type of cell into another in living mice, a big step toward the goal of growing replacement tissues to treat a variety of diseases.The cell identity switch turned ordinary pancreas cells into the rarer type that churns out insulin, essential for preventing diabetes. But its implications go beyond diabetes to a host of possibilities, scientists said.It's the second advance in about a year...

2008-08-28 18:00:51

The California Institute for Regenerative Medicine (CIRM), the state stem cell agency, issued the following statement regarding the research published today in Nature by a team from Harvard that showed it is possible to take a type of adult pancreas cell that doesn't normally produce insulin and reprogram them to produce insulin. CIRM applauds the creativity and value in the research reported and shares the excitement in the promise it might hold. However, it emphatically refutes...

2008-08-28 15:00:11

By JOHN FAUBER After more than a decade of trying to harvest the promise of embryonic stem cells, scientists have hit on a fascinating new approach that sidesteps them entirely. By adding genes to targeted cells in the body, they have been able to change the basic makeup of those cells, turning them into potential disease-curing cells. The feat, which was performed in mice, involved reprogramming cells in the pancreas that normally do not produce insulin so that they began producing the...


Word of the Day
cock-a-hoop
  • Exultant; jubilant; triumphant; on the high horse.
  • Tipsy; slightly intoxicated.
This word may come from the phrase 'to set cock on hoop,' or 'to drink festively.' Its origin otherwise is unclear. A theory, according to the Word Detective, is that it's a 'transliteration of the French phrase 'coq a huppe,' meaning a rooster displaying its crest ('huppe') in a pose of proud defiance.' Therefore, 'cock-a-hoop' would 'liken a drunken man to a boastful and aggressive rooster.'
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