Latest Drosha Stories

2010-08-16 18:20:16

Discovery furthers knowledge of microRNA's role in disease Researchers at Tufts University School of Medicine and Tufts Medical Center have identified an RNA sequence that promotes increased numbers of specific microRNAs (miRNAs), molecules that regulate cell growth, development, and stress response. The discovery helps researchers understand the links between miRNA expression and disease, including heart disease and cancer. The findings are published in the August 13 issue of Molecular...

2009-10-13 09:14:18

Berkeley Researchers Get First Look at Gene-Silencing Human RISC-Loading Complex The molecular architecture of a protein complex that helps determine the fate of human cells has been imaged for the first time by researchers with the U.S. Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab). Known as a human RISC-loading complex, this structure consists of snippets of ribonucleic acid (RNA) that control whether genetic messages are silenced or expressed. From these new...

2009-01-05 08:42:16

Two proteins play a strong role in determining the survival of ovarian cancer patients, new research shows. The study, recently published in the New England Journal of Medicine, shows when a woman has low levels of two proteins called Dicer and Drosha, her survival is much shorter than that of a woman who has high levels. The same holds true for patients with lung and breast cancer. "Very consistently, we found that low levels of Dicer in particular are predictive of poor outcomes," lead...

Word of the Day
  • Exultant; jubilant; triumphant; on the high horse.
  • Tipsy; slightly intoxicated.
This word may come from the phrase 'to set cock on hoop,' or 'to drink festively.' Its origin otherwise is unclear. A theory, according to the Word Detective, is that it's a 'transliteration of the French phrase 'coq a huppe,' meaning a rooster displaying its crest ('huppe') in a pose of proud defiance.' Therefore, 'cock-a-hoop' would 'liken a drunken man to a boastful and aggressive rooster.'