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Latest Duchenne muscular dystrophy Stories

2012-02-09 23:42:19

Twelve weeks of training geared towards improving muscular power in older people are highly effective for improving their functional capacity and quality of life, as shown by the studies carried out by the “Biomechanics and Physiology of Movement” research group at the Public University of Navarre led by Professor Mikel Izquierdo-Redin. The results of these pieces of research, conducted in collaboration with the University of Trás-os-Montes e Alto Douro (Portugal)...

2012-01-02 23:07:44

Researchers describe how increased production of a microRNA promotes progressive muscle deterioration in a mouse model of Duchenne muscular dystrophy (DMD), according to a study published online on January 2 in the Journal of Cell Biology (www.jcb.org). As DMD patients age, their damaged muscle cells are gradually replaced by collagen-rich, fibrous tissue. This muscle fibrosis is partly induced by the growth factor TGF-beta, which is highly activated in DMD patients, though exactly how...

2011-12-01 10:52:46

Researchers at the University of North Carolina at Chapel Hill have shown that it is safe to cut and paste together different viruses in an effort to create the ultimate vehicle for gene therapy. In a phase I clinical trial, the investigators found no side effects from using a "chimeric" virus to deliver replacement genes for an essential muscle protein in patients with muscular dystrophy. "This trial demonstrates that gene therapy is no longer limited by the viruses we find in nature, and...

2011-11-21 09:50:59

An international team of researchers from Leeds, London and Berlin has discovered more about the function of muscle stem cells, thanks to next-generation DNA sequencing techniques. The work, which was co-led from the University of Leeds' School of Medicine and the Charité, Berlin, is published this week in the journal Nature Genetics. The researchers investigated several families whose children suffered from a progressive muscle disease. The children developed severe...


Word of the Day
omphalos
  • The navel or umbilicus.
  • In Greek archaeology: A central boss, as on a shield, a bowl, etc.
  • A sacred stone in the temple of Apollo at Delphi, believed by the Greeks to mark the 'navel' or exact center-point of the earth.
'Omphalos' comes from the ancient Greek.
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