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Latest Early-onset Alzheimer's disease Stories

2009-10-27 16:29:20

Research has shown that diabetes increases the risk of Alzheimer's disease and the risk of memory loss in people who don't have Alzheimer's disease. But it hasn't been clear whether people with Alzheimer's disease and diabetes have more rapid memory loss than those who have Alzheimer's disease but no diabetes. New research published in the October 27, 2009, print issue of Neurology®, the medical journal of the American Academy of Neurology, suggests that those with both...

2009-09-23 09:33:04

Georgetown University researchers say they've started recruiting volunteers in the first gene therapy trial for dementia due to Alzheimer's disease. The phase II study will examine the safety and possible benefits of CERE-110, which contains a gene and is injected during surgery into a part of the brain affected by Alzheimer's disease. Researchers said the gene will instruct brain cells to produce more of a protein called Nerve Growth Factor, which helps nerve cells survive and function...

2009-09-14 10:23:50

Gothenburg researchers have discovered a previously unknown substance in spinal fluid that can be used to diagnose Alzheimer's disease. The findings, described in a thesis from the Sahlgrenska Academy at the University of Gothenburg, Sweden, will also be useful in research on new medications. The substance is a beta-amyloid protein called Abeta16. The thesis shows in two independent studies that Alzheimer's patients have higher levels of the protein in their spinal fluid than do healthy...

2009-09-08 14:12:57

An international team of scientists led by Cardiff University in Wales has reported finding two more genetic risk factors of Alzheimer's disease. The group said it completed the largest genome-wide association study ever involving patients with Alzheimer's disease. The study pooled DNA samples from more than 19,000 older European and U.S. residents. The researchers said previously only four genes had been definitively associated with Alzheimer's disease -- three genetic mutations identified...

2009-09-08 07:12:19

Getting a cold, stomach bug or other infection may lead to increased memory loss in people with Alzheimer's disease, according to research published in the September 8, 2009, print issue of Neurology®, the medical journal of the American Academy of Neurology. The study found that people who had respiratory, gastrointestinal or other infections or even bumps and bruises from a fall were more likely to have high blood levels of tumor necrosis factor-ÃŽ±, a...

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2009-09-07 06:45:00

An international team of scientists has identified two more genetic risk factors for Alzheimer's disease. The findings are reported in the online edition of the journal Nature Genetics. The group, led by investigators from the School of Medicine at Cardiff in the United Kingdom and including scientists from Washington University School of Medicine in St. Louis, completed the largest genome-wide association study ever involving patients with Alzheimer's disease. The study pooled DNA samples...

2009-09-04 16:24:53

U.S., South Korean and French researchers report their discovery of a protein fragment that may result in new Alzheimer's drugs. The research, published by Federation of American Societies for Experimental Biology Journal, found the N60 section of a protein called RanBP9 may be key to creating a drug that could help reduce production of the excessive amounts amyloid beta proteins associated with Alzheimer's. Our study suggests that targeting RanBP9 expression and/or N60 fragment generation...

2009-08-13 13:21:35

U.S. researchers say they have linked oxygen treatment during surgery to hastened memory loss in mice. The study, published in NeuroReport, suggests elderly patients genetically predisposed to Alzheimer's disease who receive high concentration of oxygen because of surgery may start exhibiting symptoms of Alzheimer's disease sooner. Gary Arendash of the University of Southern Florida in Tampa and Dr. Jackson Roberts II of Vanderbilt University in Nashville exposed mice genetically altered to...

2009-08-11 07:30:22

A University of California Irvine study has found that a gene called TOMM40 appears twice as often in people who develop Alzheimer's disease as it does in those who don't. Alzheimer's, for which there is no cure, is the leading cause of elderly dementia. Having the harmful form of TOMM40 significantly increases one's susceptibility when other risk factors, such as having a gene called ApoE-4, are present, the new study reports. People who have ApoE-4 are three to eight times more likely to...

2009-08-07 15:09:48

A recently discovered gene appears twice as often in people with Alzheimer's disease than in those without it, researchers in California said. Alzheimer's is the leading cause of elderly dementia and so far scientists have found no cure. The TOMM40 gene, discovered by researchers at the University of California, Irvine, significantly increases the susceptibility of Alzheimer's when other risk factors -- such as having a gene called ApoE-4 -- are present, said Dr. Steven Potkin, lead author of...


Word of the Day
cenobite
  • One of a religious order living in a convent or in community; a monk: opposed to anchoret or hermit (one who lives in solitude).
  • A social bee.
This word comes from the Latin 'coenobium,' convent, which comes from the Greek 'koinobios,' living in community.
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