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Latest Early-onset Alzheimer's disease Stories

2009-05-21 08:53:00

KIRKLAND, Wash., May 21 /PRNewswire/ -- Advana Science (www.advanascience.com) announced that Mark A. Smith, PhD, a leading researcher in Alzheimer's disease, has been named scientific advisor to the Company. According to the Journal of Alzheimer's Disease (Volume 16, Issue 3), Dr. Smith was ranked third in the world among the Top 100 Alzheimer's disease investigators in March 2009. Dr. Smith brings over 20 years of research experience focused on investigating the pathological mechanisms...

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2009-04-14 14:27:50

British researchers have developed a new drug against Alzheimer's disease they say has shown promise in tests on a handful of patients, Reuters reported. The small molecule drug (called CPHPC) caused the disappearance of a protein called serum amyloid P component (SAP), thought to be involved in the disease, from the brains of five Alzheimer's patients who took it for three months, according researchers from the University College London. The team said SAP is always present in both the...

2009-04-11 08:30:20

A recent study by Mount Sinai faculty suggests that a gene associated with onset of type-2 diabetes also decreases in Alzheimer's disease dementia cases. The research, led by Dr. Giulio Maria Pasinetti, MD, Ph.D., The Aidekman Family Professor in Neurology, and Professor of Psychiatry and Geriatrics and Adult Development at Mount Sinai School of Medicine, was published this week in the scientific journal, Archives of Neurology. "This new evidence is of extreme interest," Dr. Pasinetti tells...

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2009-03-24 12:01:50

A new report suggests the health care costs of Alzheimer's disease patients are more than triple those of other older people, the Associated Press reported. The report showed that those costs don't even include the billions of hours of unpaid care from family members. Alzheimer's sufferers are more often hospitalized and treated in skilled-nursing centers than those aged 65 and older without the mind-destroying disease. Alzheimer's medical costs also often include nursing home care and...

2009-02-20 12:59:38

A study from the Buck Institute for Age Research offers a revolutionary new model for Alzheimer's disease (AD), a devastating neurodegenerative disorder which afflicts 24 million people worldwide. In an effort to unravel the normal function of a protein implicated in AD, scientists in California and France have discovered a naturally occurring protein that provides a new therapeutic target for the disease. The finding upsets the current theory that AD is a disease of toxicity stemming from...

2009-02-18 07:05:00

WASHINGTON, Feb. 18 /PRNewswire-USNewswire/ -- The winners of the MetLife Foundation Awards for Medical Research in Alzheimer's Disease will be announced in Washington, D.C. today, at a scientific briefing and luncheon that honors two scientists whose groundbreaking research has led to significant understanding of Alzheimer's and the substances in the brain that play an important role in the disease. The awardees are Michael S. Wolfe, Ph.D., professor of neurology at Harvard Medical School...

2009-01-12 09:21:02

Researchers at Mayo Clinic have discovered the first gender-linked susceptibility gene for late-onset Alzheimer's disease. In the Jan. 11 online edition of Nature Genetics, they report the results of their two-stage genome-wide association study of patients with Alzheimer's disease. The research showed that women who inherited two copies of a variant in the PCDH11X gene, found on the X chromosome, are at considerably greater risk of developing Alzheimer's disease. Women with a variant on one...

2009-01-06 14:51:25

Mutation of a gene that helps proteins migrate in and out of the cell's genetic command center "“ the nucleus "“ puts some families at higher risk for the degenerative brain disease acute necrotizing encephalopathy (ANE). This is the conclusion of a global study to be published Jan. 9 by the American Journal of Human Genetics, and currently posted online, that was led by a researcher from Cincinnati Children's Hospital Medical Center. Researchers investigated cases where otherwise...

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2009-01-01 13:42:15

Scientists have new information about the complex genetic signature associated with Alzheimer's disease, the leading cause of cognitive decline and dementia in the elderly. The research, published by Cell Press in the January issue of the American Journal of Human Genetics, uses a powerful, high-resolution analysis to look for genes associated with this devastating neurodegenerative disorder. Previous research linked late-onset Alzheimer's disease, the most common form, with the...

2008-12-22 09:21:47

Researchers have found that two proteins which work in tandem in the brain's blood vessels present a double whammy in Alzheimer's disease. Not only do the proteins lessen blood flow in the brain, but they also reduce the rate at which the brain is able to remove amyloid beta, the protein that builds up in toxic quantities in the brains of patients with the disease. The work, described in a paper published online Dec. 21 in the journal Nature Cell Biology, provides hard evidence directly...


Word of the Day
humgruffin
  • A terrible or repulsive person.
Regarding the etymology of 'humgruffin,' the OED says (rather unhelpfully) that it's a 'made-up word.' We might guess that 'hum' comes from 'humbug' or possibly 'hum' meaning 'a disagreeable smell,' while 'gruffin' could be a combination of 'gruff' and 'griffin.'