Latest Early-onset Alzheimer's disease Stories
Researchers have identified a gene that appears to increase a person's risk of developing late-onset Alzheimer's disease, the most common form of the disease. The gene, abbreviated as MTHFD1L, is on chromosome six, and was identified in a genome-wide association study. Details are published September 23 in the journal PLoS Genetics.The collaborative team of researchers was led by Margaret A. Pericak-Vance, PhD, Director of the John P. Hussman Institute for Human Genomics at the University of...
Neurological researchers at Rush University Medical Center have found a new therapeutic target that can potentially lead to a new way to prevent the progression of Alzheimer's disease. The target called neutral sphingomyelinase (N-SMase) is a protein that when activated, can cause a chain of reactions in the cell leading to neuronal death and memory loss.Results from the study funded by the National Institutes of Health and the Alzheimer's Association will be published in the September 22...
By Jim Dryden, Washington University in St. LouisAn international team of Alzheimer's disease experts, led by Washington University School of Medicine in St. Louis, has uncovered a gene variation that appears to predict the rate at which Alzheimer's disease will progress.The investigators report their findings online in the journal Public Library of Science (PLoS) Genetics.Whereas previous studies have focused on factors that influence the risk for Alzheimer's, the new research points to a...
A gene variation that appears to predict the rate at which Alzheimer's disease will progress has been uncovered by an international team of Alzheimer's disease experts, led by Washington University School of Medicine in St. Louis. Published in the open-access journal PLoS Genetics, the findings help determine how rapidly Alzheimer's patients may develop full-blown dementia after their diagnosis.Alzheimer's disease, one of the most common neurodegenerative disorders, affects over 4.5 million...
NEW YORK, Sept. 1 /PRNewswire-USNewswire/ -- Researchers at the Fisher Center for Alzheimer's Disease Research laboratory today published "Gamma-secretase Activating Protein is a Therapeutic Target for Alzheimer's Disease" in Nature online. Drs. Gen He (lead author) and Paul Greengard have discovered a protein that stimulates the production of beta-amyloid, and therefore represents a major new advance in Alzheimer's disease research. The protein, called gamma-secretase activating protein...
HONOLULU, July 14 /PRNewswire-USNewswire/ -- This week, nearly 4,000 scientists from around the world gathered to report and discuss the latest advances in research on treatments, risk factors, and diagnosis for the health epidemic of the 21st century - Alzheimer's disease - at the Alzheimer's Association's 2010 International Conference on Alzheimer's Disease (AAICAD 2010) in Honolulu. "With an aging baby boomer generation, the Alzheimer's disease crisis will continue to touch more lives...
- - New Alzheimer's Risk Gene May Affect Memory Scores and Brain Atrophy in Middle Age - - Clinical Trial of Intranasal Insulin Shows Benefits in Alzheimer's and MCI - - Known Alzheimer's Risk Gene May Change Shape of Brain Deposits - HONOLULU, July 14 /PRNewswire-USNewswire/ -- Last minute scientific submissions to the Alzheimer's Association International Conference on Alzheimer's Disease 2010 (AAICAD 2010) in Honolulu, HI, known as "hot topics," suggest that (1) a newly-discovered risk...
- Global Impact Could Multiply As The Population Continues to Age - HONOLULU, July 13 /PRNewswire-USNewswire/ -- Having Alzheimer's disease may increase the risk of getting other potentially disabling health conditions, including seizures and anemia, according to new research presented today at the Alzheimer's Association International Conference on Alzheimer's Disease 2010 (AAICAD 2010) in Honolulu, HI. "Alzheimer's disease is a global health crisis with devastating effects on...
- When Combined with a Known Alzheimer's Gene, Your Alzheimer's Risk may be Doubled - HONOLULU, July 12 /PRNewswire-USNewswire/ -- A gene known as FTO, which appears to be correlated with obesity in humans, may also increase risk of Alzheimer's disease and dementia, according to new research presented today at the Alzheimer's Association International Conference on Alzheimer's Disease 2010 (AAICAD 2010) in Honolulu, HI. And when a person has certain variants of both FTO and a recognized...
New research has identified the memory and brain scan tests that appear to predict best whether a person with cognitive problems might develop Alzheimer's disease. The research is published in the June 30, 2010, online issue of Neurology®, the medical journal of the American Academy of Neurology.Memory and brain scan tests were performed on 85 people with mild cognitive impairment (MCI) who were part of a larger study called the Alzheimer's Disease Neuroimaging Initiative. The tests...
