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Latest Eicosanoids Stories

2014-07-30 23:16:49

Dignity Sciences Limited finds that orally administered DGLA distributes well to the skin resulting in high dermal bioavailability Dublin, Ireland (PRWEB) July 30, 2014 Dignity Sciences Limited, a privately held biopharmaceutical company, today announced the successful completion of a Phase I trial with DS107G, an oral formulation of Dihomo Gamma Linolenic Acid (DGLA). This study was a randomized, placebo-controlled, double-blind, single-ascending and multiple dose Phase I clinical trial...

2014-05-28 08:39:41

Friedrich Schiller University Jena Pharmacists develop three new drug candidates against inflammation It is something like the police force of our body: the immune system. It disables intruding pathogens, it dismantles injured tissue and boosts wound healing. In this form of 'self-defense' inflammatory reactions play a decisive role. But sometimes the body's defense mechanism gets out of control and cells or tissues are affected: "Then excessive reactions can occur and illnesses along...

2014-01-08 12:30:46

ATLANTA, Jan. 8, 2014 /PRNewswire/ -- The Celtaxsys Board of Directors today announced that Greg Duncan has been appointed as President and Chief Executive Officer (CEO) and will join the board of directors effective immediately. Mr. Duncan joins Celtaxsys following his most recent role as an Executive Committee member and President of North America for Brussels based UCB, prior to which he served as a Senior Vice-President at Pfizer where his duties included leading US marketing, as...

2013-05-28 21:52:37

Resolvins are molecules naturally produced by the body from omega-3 fatty acids — a process that can be jumpstarted by common aspirin. In a new study, published in The FASEB Journal, researchers at Karolinska Institutet describe how resolvins could protect against the cognitive impairment that often affects recovery of surgical and critically ill patients. The study adds new knowledge on how peripheral surgery affects the brain and neuronal function contributing to the processes of...

Asthma Treatment Uses Double Duty Molecule
2013-02-28 09:06:31

redOrbit Staff & Wire Reports - Your Universe Online Researchers at the Brigham and Women´s Hospital (BWH) in Boston have discovered a molecule that controls cells responsible for decreasing airway inflammation in asthma patients, and their discovery could lead to new treatments for the millions of Americans that suffer from the disease. The molecule is known as lipoxin A4, and according to the researchers, it is responsible for resolving inflammation. It accomplishes this in...

Image 1 - Mass Extinctions: Nature’s Spectacular Staging of Natural Selection
2012-02-11 04:00:32

In “Mass Extinctions: Nature´s Spectacular Staging of Natural Selection” Julian Lieb, M.D  provides evidence that “die-offs” or mass deaths are episodes of natural selection, caused by activation of enzymes of the arachidonic acid cascade. In prior publications, Dr Lieb showed that products of the arachidonic acid cascade are the agents of natural selection and evolution, differentiating between infertility and reproduction, and between health and...

2011-12-19 16:05:38

Recent findings in mice suggest that blocking the production of small molecules produced in the body, known as epoxyeicosatrienoic acids (EETs), may represent a novel strategy for treating cancer by eliminating the blood vessels that feed cancer tumors. This research is the first to show that EETs work in concert with vascular endothelial growth factor (VEGF), a protein known to induce blood vessel growth. Together, EETs and VEGF promote metastasis, or the spread of cancer, by encouraging the...

2011-12-19 15:06:25

Study documents connection between increased levels of these lipids and cancer growth and metastasis; also opens door to new avenue for cancer treatment A group of small molecules called EETs — currently under scrutiny as possible treatment targets for a host of cardiovascular diseases — may also drive the growth and spread of cancer, according to researchers at the Dana-Farber/Children's Hospital Cancer Center (DF/CHCC) and other institutions. Their findings also raise the...

2011-12-19 15:03:01

Drugs that enhance levels of small molecules derived naturally in the body from a major component of animal fats (small molecules known as epoxyeicosatrienoic acids [EETs]) are currently in clinical trials for the treatment of high blood pressure and diabetes. A team of researchers – led by Dipak Panigrahy and Mark Kieran, at the Dana-Farber Cancer Institute, Boston; Sui Huang, at the Institute for Systems Biology, Seattle; and Darryl Zeldin, at the National Institute of Environmental...

2011-01-10 07:00:00

CAMBRIDGE, Mass. and NEW YORK, Jan. 10, 2011 /PRNewswire/ -- Resolvyx Pharmaceuticals (Resolvyx) and Celtic Therapeutics Holdings L.P. (Celtic Therapeutics), a successor firm to Celtic Pharma, announced today that they have entered into a final agreement under which Celtic Therapeutics has acquired and licensed worldwide rights related to Resolvyx's RX-10045, a late-stage program for the treatment of dry eye syndrome and other ophthalmic conditions. Terms of the deal include upfront...


Word of the Day
omphalos
  • The navel or umbilicus.
  • In Greek archaeology: A central boss, as on a shield, a bowl, etc.
  • A sacred stone in the temple of Apollo at Delphi, believed by the Greeks to mark the 'navel' or exact center-point of the earth.
'Omphalos' comes from the ancient Greek.
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