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Latest Elastase Stories

2014-03-13 08:28:44

Study suggests that the phytonutrient-rich plant-based material exerts inhibitory activity on human neutrophil elastase (HNE). MOMENCE, Ill., March 13, 2014 /PRNewswire/ -- FutureCeuticals, Inc. announced publication of a double-blind, cross-over, placebo-controlled clinical study performed on 20 healthy subjects who had been served a single serving of 50mg of its proprietary Dermaval(TM) ingredient. The results showed a statistically significant inhibition of Human Neutrophil...

2011-04-22 12:53:10

Transplanting cells from healthy adult livers may work in treating a genetic liver-lung disorder that affects millions of people worldwide, according to an animal study in the April 18 online edition of the Journal of Clinical Investigation. Jayanta Roy-Chowdhury, M.D. , professor of medicine and of genetics at Albert Einstein College of Medicine of Yeshiva University, is the study's senior author. The genetic disorder, alpha-1 antitrypsin (AAT) deficiency, is the most common potentially...

2011-01-05 13:12:00

MIAMI, Jan. 5, 2011 /PRNewswire/ -- The Alpha-1 Foundation announced today that it has awarded two research grants to investigators whose research will contribute to our understanding of the causes and mechanisms that give rise to lung disease. The first grant will investigate how cigarette smoke promotes the onset of emphysema through the destruction of elastic fibers in the lung, and how the alpha(1)-proteinase inhibitor (A1PI) protein protects the elastic fibers from degradation. The...

2010-05-26 06:30:00

BEDFORD, Mass. and WARSAW, Poland, May 26 /PRNewswire/ -- VisEn Medical Inc., a leader in fluorescence in vivo imaging from research through medicine, announced the commercial launch of two new imaging agents -- ProSense® 750 FAST for expanded versatility in imaging cathepsin activity, and Neutrophil Elastase(TM) 680 FAST, for imaging of inflammatory elastase activity associated with disease progression and therapeutic response. The launch announcements were made at the...

2009-01-02 15:13:10

A team of scientists has discovered a new syndrome associated with severe congenital neutropenia (SCN), a rare disorder in which children lack sufficient infection-fighting white cells, and identified the genetic cause of the syndrome: mutations in the gene Glucose-6-phosphatase, catalytic subunit 3 (G6PC3). The findings, which are published in the Jan. 1, 2009 issue of The New England Journal of Medicine, were made by an international team of scientists, composed of 14 researchers from the...

2008-12-15 09:52:36

An anti-cancer compound found in broccoli and cabbage works by blocking a key enzyme associated with rapidly advancing cancer. The compound found in the veggies, indole-3-carbinol, is already in human clinical trials because of its ability to stop breast and prostate cancer growth in mice. The new findings are the first to explain how indole-3-carbinol stops cell growth. Researchers at the University of California, Berkeley, showed that indole-3-carbinol inhibits the enzyme elastase. Elastase...

2008-10-13 09:00:09

Kamada, a biopharmaceutical company, has reported positive data from its Phase II study evaluating inhaled Alpha-1 Antitrypsin delivered via an investigational eFlow Nebulizer System, in the treatment of cystic fibrosis. The results demonstrate the product has an excellent safety profile and shows promising signs of efficacy, as indicated by a reduction in lung inflammation, the company said. The Phase II trial was a double-blind, placebo-controlled study, performed at the Cystic Fibrosis...

2008-10-01 12:00:06

Arriva Pharmaceuticals, a biopharmaceutical company focused on developing anti-inflammatory therapies, announced today that it had been granted a patent in the U.S. for methods to produce certain proteins in yeast. Among the proteins whose production is covered by the patent (United States Patent 7,419,801) is recombinant alpha 1-antitrypsin (rAAT), the protein used in Respriva(TM), the company's lead product. "This patent extends our patent portfolio and strengthens our intellectual...

2008-09-05 03:00:06

By Snyder, Marion L Fantz, Corinne R; Dahl, Morten; Snyder, Melissa R; Highsmith, W Edward Jr CASE A 52-year-old white woman with a presumptive diagnosis of cirrhosis attributed to nonalcoholic steatohepatitis was referred for a liver transplant consultation. The patient reported increased abdominal discomfort, swelling, and lower extremity edema beginning 7 years earlier, as well as intermittent nausea, weakness, and confusion which had increased in frequency during the previous year....

2005-07-13 15:00:00

ANN ARBOR, Mich. - Each year, 200,000 Americans find out that the largest blood vessel in their body, the aorta, may burst open at any time. About 20,000 die suddenly from such a rupture. And another 36,000 have surgery to repair or replace the swelling section of aorta before time runs out. But despite the deadly toll of this condition, called abdominal aortic aneurysm or AAA ("triple A"), experts know very little about why it happens. Now, a pair of papers from researchers at the...


Word of the Day
vermicular
  • Like a worm in form or movement; vermiform; tortuous or sinuous; also, writhing or wriggling.
  • Like the track or trace of a worm; appearing as if worm-eaten; vermiculate.
  • Marked with fine, close-set, wavy or tortuous lines of color; vermiculated.
  • A form of rusticated masonry which is so wrought as to appear thickly indented with worm-tracks.
This word ultimately comes from the Latin 'vermis,' worm.
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