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Last updated on April 24, 2014 at 1:21 EDT

Latest Endocannabinoid system Stories

2012-04-27 00:01:19

The ability to navigate using spatial cues was impaired in mice whose brains were minus a channel that delivers potassium – a finding that may have implications for humans with damage to the hippocampus, a brain structure critical to memory and learning, according to a Baylor University researcher. Mice missing the channel also showed diminished learning ability in an experiment dealing with fear conditioning, said Joaquin Lugo, Ph.D., the lead author in the study and an assistant...

2012-03-08 15:57:15

A new study lead by the Neuroscience Institute of Alicante reveals how manipulating the endocannabinoid system can modulate high levels of impulsivity. This is the main problem in psychiatric illnesses such a schizophrenia, bipolar disorder and substance abuse. Spanish researchers have for the first time proved that the CB2 receptor, which has modulating functions in the nervous system, is involved in regulating impulsive behavior. "Such a result proves the relevance that manipulation...

2012-03-06 23:06:47

UCI-led study points to role endocannabinoids play in energy metabolism Stop exercising, eat as much as you want ... and still lose weight? It sounds impossible, but UC Irvine and Italian researchers have found that by blocking a natural, marijuana-like chemical regulating energy metabolism, this can happen, at least in the lab. To create this hypermetabolic state, UCI pharmacology professor Daniele Piomelli and colleagues engineered neurons in the forebrains of mice to limit production...

2012-03-05 10:40:19

A deterioration of working memory is observed in people who consume drugs containing cannabinoid compounds found in cannabis leaves and buds. A team led by Giovanni Marsicano (Inserm Research Unit 862) in collaboration with a team led by Xia Zhang, has recently identified the mechanism by which these substances affect working memory. These researchers have demonstrated for the first time that the adverse effect of cannabinoids on working memory is exerted via receptors located in the glial...

2012-03-02 01:30:30

A major downside of the medical use of marijuana is the drug's ill effects on working memory, the ability to transiently hold and process information for reasoning, comprehension and learning. Researchers reporting in the March 2 print issue of the Cell Press journal Cell provide new insight into the source of those memory lapses. The answer comes as quite a surprise: Marijuana's major psychoactive ingredient (THC) impairs memory independently of its direct effects on neurons. The side...

2011-07-12 12:49:29

Researchers from the Universities of Bonn and Mainz discover a mechanism that can protect from aging processes Humans are getting older and older, and the number of people with dementia is increasing. The factors controlling degeneration of the brain are still mostly unknown. However, researchers assume that factors such as stress, accumulation of toxic waste products as well as inflammation accelerate aging. But, vice versa, there are also mechanisms that can - like a bodyguard - protect the...

2011-06-07 06:28:14

(Ivanhoe Newswire) -- Definitive proof of an adverse effect of chronic marijuana use could lead to potential drug treatments and aid other research involved in cannabinoid receptors, a neurotransmission system receiving a lot of attention. Scientists used molecular imaging to visualize changes in the brains of heavy marijuana smokers versus non-smokers and found that abuse of the drug led to a decreased number of cannabinoid CB1 receptors, which are involved in not just pleasure, appetite and...

2011-06-06 20:00:52

Chronic use of marijuana causes a decrease in brain receptors that bind with the psychoactive chemical in cannabis Definitive proof of an adverse effect of chronic marijuana use revealed at SNM's 58th Annual Meeting could lead to potential drug treatments and aid other research involved in cannabinoid receptors, a neurotransmission system receiving a lot of attention. Scientists used molecular imaging to visualize changes in the brains of heavy marijuana smokers versus non-smokers and found...

2011-05-12 07:28:58

(Ivanhoe Newswire) -- Scientists have discovered a new role for a biological pathway that not only signals the body's metabolic response to nutritional changes but also affects lifespan. The researchers conducted the study on Caenorhabditis elegans (nematodes). Dietary restriction is a way to extend lifespan and postpone age-related diseases in many species including yeast, worms, flies and rodents. However, researchers have been unclear about the molecular signals involved until this study....

2011-05-11 23:50:26

New discovery advances study of diet and longevity A team led by a scientist from the Florida campus of The Scripps Research Institute has identified a new role for a biological pathway that not only signals the body's metabolic response to nutritional changes, but also affects lifespan. The study, published in the May 12, 2011 issue of the journal Nature, was conducted on Caenorhabditis elegans (nematodes or roundworms), which are a widely accepted model for human aging research. "Not only...