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Latest Endocannabinoid system Stories

2011-05-11 23:46:03

Research identifies novel metabolic signaling pathway in worms that coordinates the aging response to nutrient availability There is no longer any doubt that dietary restriction (DR) extends lifespan. Many studies have shown that limiting nutrient intake extends lifespan in yeast, worms, flies and as well as postponing age-related diseases in mice. However, scientists are still puzzling over the exact mechanism of DR, convinced its secrets are the key to new therapies for diseases such as...

2011-02-04 12:39:41

The link between deficits of omega-3 poly-unsaturated fatty acids (AGPO-3) and the onset of depressive disorders is not new in the medical field. However, what has not been known until now is the brain mechanism by which diet can condition mental health to a certain extent. Research undertaken by scientists in Bordeaux (France) and at the Faculty of Medicine and Odontology of the University of the Basque Country (UPV/EHU) and published in Nature Neuroscience, provides new clues to...

2010-11-17 21:04:31

Research in animal models focuses on area of the brain that controls emotion, social behavior Many mental health disorders, such as autism and schizophrenia, produce changes in social behavior or interactions. The frequency and/or severity of these disorders is substantially greater in boys than girls, but the biological basis for this difference between the two sexes is unknown. Researchers at the University of Maryland School of Medicine have discovered differences in the development of the...

2010-09-20 22:35:07

Drug created by UCI, Italian team inhibits enzyme that breaks down anandamide American and Italian researchers have found that a novel drug allows anandamide "“ a marijuana-like chemical in the body "“ to effectively control pain at the site of an injury. Led by Daniele Piomelli, the Louise Turner Arnold Chair in Neurosciences and director of the Center for Drug Discovery at UC Irvine, the study suggests that such compounds could form the basis of pain medications that don't...

2010-05-13 11:03:39

The new research suggests potential target for drugs to combat alcohol addiction In findings that should finally put to rest a decade of controversy in the field of neurobiology, a team at The Scripps Research Institute has found decisive evidence that a specific neurotransmitter system"”the endocannabinoid system"”is active in a brain region known to play a key role in the processing of memory, emotional reactions, and addiction formation. The new study also shows that this...

2009-12-22 14:07:16

Endocannabinoid modulation of tongue sweet taste receptors may help control feeding behavior New findings from the Monell Center and Kyushu University in Japan report that endocannabinoids act directly on taste receptors on the tongue to enhance sweet taste. "Our taste cells may be more involved in regulating our appetites than we had previously known," said study author Robert Margolskee, M.D., Ph.D., a Monell molecular biologist. "Better understanding of the driving forces for eating and...

2009-01-21 15:40:40

Human male fertility may be impacted by long-term exposure to marijuana, researchers in the United States and Japan suggest. The researchers at Vanderbilt University Medical Center in Nashville and colleagues said the findings show that genetic loss of fatty acid amide hydrolase -- an enzyme -- results in elevated levels of anandamide, an endocannabinoid, in the male reproductive system, leading to compromised fertilizing capacity of sperm. The endocannabinoid system refers to a group of...

2008-11-20 09:07:40

A new study makes the case for an illegal drug by showcasing its potential protective effects against Alzheimer's disease. New research suggests a legal drug similar to tetrahydrocannabinol (THC), the main psychoactive substance in marijuana, may help prevent or delay the onset of Alzheimer's disease. The synthetic drug WIN-55212-2 (WIN) was shown to reduce brain inflammation and encourage the formation of new brain cells in rats. WIN is not used in humans yet because of its tendency to...

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2008-11-19 15:40:00

The more research they do, the more evidence Ohio State University scientists find that specific elements of marijuana can be good for the aging brain by reducing inflammation there and possibly even stimulating the formation of new brain cells.The research suggests that the development of a legal drug that contains certain properties similar to those in marijuana might help prevent or delay the onset of Alzheimer's disease. Though the exact cause of Alzheimer's remains unknown, chronic...

2008-08-27 12:00:34

U.S. scientists say they have created a synthetic molecule that could be used to treat chronic pain in patients with diseases such as diabetes or shingles. Northeastern University Professor Alexandros Makriyannis, Associate Professor Torjjorn Jarbe and former University of Connecticut researchers Chen Li and Qian Liu said their new molecule, AM1346, mimics, but is more powerful than, anandamide, an endogenous cannabinoid neurotransmitter found prominently in the brains of humans and...


Word of the Day
Cthulhu
  • A gigantic fictional humanoid alien god being described with a head resembling an octopus and dragon wings and claws, around whom an insane cult developed.
  • Pertaining to the mythos of Cthulhu and additional otherworldly beings created by H. P. Lovecraft or inspired by his writings and imitators.
This word was invented in 1926 by H.P. Lovecraft for his short story, 'The Call of Cthulhu.' 'Cthulhu' may be based on the word 'chthonic,' which in Greek mythology refers to the underworld.
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