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Latest Endothelial progenitor cell Stories

2011-01-19 23:43:29

Blood-vessel cells can combat aggressive tumors, helping to prevent them from spreading through the body, new study finds MIT scientists have discovered that cells lining the blood vessels secrete molecules that suppress tumor growth and keep cancer cells from invading other tissues, a finding that could lead to a new way to treat cancer. Elazer Edelman, professor in the MIT-Harvard Division of Health Sciences and Technology (HST), says that implanting such cells adjacent to a patient's tumor...

2011-01-04 08:00:00

FT. LAUDERDALE, Fla., Jan. 4, 2011 /PRNewswire/ -- OrbusNeich today announced that the United States Patent and Trademark Office (USPTO) has granted an additional patent expanding protection of the company's Genous endothelial progenitor cell (EPC) capture technology. The patent (U.S. Pat. No. US 7,803,183) covers a coating on an implantable medical device that has one or more layers of a matrix. Incorporated into the matrix are antibodies or antibody fragments that allow for capture in...

2010-11-23 07:00:00

HONG KONG, Nov. 23, 2010 /PRNewswire/ -- OrbusNeich today announced that data from two studies demonstrate that the Genous Stent increases endothelial coverage and reduces thrombogenicity as compared to bare metal stents (BMS) by enhancing the specific binding of CD34+ endothelial progenitor cells (EPCs). Eric J. Duckers, M.D., Ph.D., of the Thoraxcenter at Erasmus University Medical Center in Rotterdam, The Netherlands, and co-investigators Saami Yazdani, Ph.D., and Renu Virmani, M.D.,...

2010-08-13 16:01:10

Isolating cells from a patient's blood or bone marrow that nourish blood vessels may be a safer and less arduous route to treatment of cardiovascular disease than obtaining rare stem cells, according to research from Emory University School of Medicine. In recent clinical trials, doctors in several countries have tested the ability of a patient's bone marrow cells to repair damage, such as heart attacks and peripheral artery disease, created by problems of blood flow. "The focus has been on...

2010-07-06 07:00:00

MCLEAN, Va., July 6 /PRNewswire/ -- New findings indicate that cocoa flavanols may be an important part of a healthy diet for people with cardiovascular disease, which affects more than 80 million Americans, according to research by a team of internationally-renowned researchers, including scientists from Mars, Incorporated. The breakthrough study conducted at the University of California San Francisco and published in the prestigious Journal of the American College of Cardiology...

2010-06-03 16:35:54

By capturing movies of both the blood and vasculature of zebrafish embryos, each less than two millimeters long, researchers have been able for the first time to see the very moment that blood begins to flow. The observations, reported online on June 3rd in Current Biology, a Cell Press publication, show that the earliest blood flow, involving what appear to be hundreds of cells, begins all at once. Remarkably, that onset of life-giving circulation takes more than a beating heart. In fact,...

2010-04-08 09:10:37

A nutritional supplement could stimulate the production of stem cells integral for repairing the body. Research published in BioMed Central's open access Journal of Translational Medicine suggests that a commercially-available supplement can increase the blood circulation of hematopoietic stem cells, which can give rise to all blood cells, and endothelial progenitor cells, which repair damage to blood vessels. Thomas E. Ichim from Medistem Incorporated, USA worked with a team of 13...

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2010-03-05 09:05:00

Promises broad clinical benefits, from bone marrow transplantation to therapies for heart, brain, skin and lungs In a leap toward making stem cell therapy widely available, researchers at the Ansary Stem Cell Institute at Weill Cornell Medical College have discovered that endothelial cells, the most basic building blocks of the vascular system, produce growth factors that can grow copious amounts of adult stem cells and their progeny over the course of weeks. Until now, adult stem cell...

2010-02-23 10:25:21

Glioblastoma is one of the most deadly human brain cancers. Radiation can temporarily shrink a tumor, but they nearly always recur within weeks or months and few patients survive longer than two years after diagnosis. Now scientists at the Stanford University School of Medicine studying the tumor in mice have found a way to stop the cancer cells from growing back after radiation by blocking its access to oxygen and nutrients. The discovery happened when the researchers realized that...

2010-02-03 22:39:03

Researchers at the Pontifícia Universidade Cat³lica do Paraná and Instituto Carlos Chagas have evaluated the therapeutic potential of purified and expanded CD133+ cells human umbilical cord blood (HUCB)-derived in treating myocardial infarction by intramyocardially injecting them into a rat model. Patients who have high cardiovascular risks have fewer endothelial progenitor cells (EPCs) and their EPCs exhibit greater in vitro senescence. HUCB-derived EPCs could be...