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Latest Enzyme Stories

2011-12-08 23:39:57

Scientists at Warwick Medical School have made an important discovery about the mechanism controlling the body´s ℠fat switch´, shedding new light on our understanding of how proteins regulate appetite control and insulin secretion. This research, led by Professor Victor Zammit, Head of Metabolic and Vascular Health at Warwick Medical School, found that the enzyme known as ℠Carnitine palmitoyltransferase 1A´ (CPT1) has a switch which is thrown depending on the...

2011-12-08 23:36:11

Findings explain the molecular basis for cherubism disease and may open new avenues for inhibiting Tankyrase function in cancer therapy The Samuel Lunenfeld Research Institute's Drs. Frank Sicheri, Tony Pawson and Sebastian Guettler, in collaboration with Dr. Robert Rottapel at the Ontario Cancer Institute, have uncovered the detailed architecture of a crucial component of Tankyrase, a protein linked to the bone development disorder cherubism and involved in a myriad of cellular processes....

2011-12-07 14:30:26

Supercomputer simulations at the Department of Energy's Oak Ridge National Laboratory are giving scientists unprecedented access to a key class of proteins involved in drug detoxification. Jerome Baudry and Yinglong Miao, who are jointly affiliated with ORNL and the University of Tennessee, have performed simulations to observe the motions of water molecules in a class of enzymes called P450s. Certain types of P450 are responsible for processing a large fraction of drugs taken by humans....

2011-12-06 12:37:12

Scientists at the European Commission's Joint Research Centre (JRC) have identified a shortlist of denaturants that could be used to harmonize denaturing practices at EU level and reduce fraud and tax evasion of alcoholic beverages. The proposed denaturants could potentially replace over 100 different substances currently used in Member States to denature alcohol. Denaturants are used to make alcohol unfit for human consumption and are therefore strong-smelling or bitter-tasting...

2011-11-22 11:33:19

Implications for biofuels University of Georgia researchers have discovered that two proteins come together in an unexpected way to make a carbohydrate, a chain of sugar molecules, in plant cell walls. This fundamental discovery changes the way scientists think about how plant cell walls are made and opens a new door to converting plants to biofuels and other carbon-based products. In 2006, the UGA research team, led by Debra Mohnen, a faculty member in the UGA Complex Carbohydrate...

2011-11-14 15:15:10

UC San Diego researchers find surprising role for enzyme in tumor cell division and new drug to combat it Researchers at the University of California, San Diego School of Medicine and the UC San Diego Moores Cancer Center have identified a new drug discovery approach enabling the destruction of the most highly proliferative tumors. The discovery, published in the Nov. 13 online issue of the journal Nature Medicine, points to an effective, alternative method for killing fast-growing cancer...

2011-11-09 10:31:34

A tree outside Oak Ridge National Laboratory researcher Pratul Agarwal's office window provided the inspiration for a discovery that may ultimately lead to drugs with fewer side effects, less expensive biofuels and more. Just as a breeze causes leaves, branches and ultimately the tree to move, enzymes moving at the molecular level perform hundreds of chemical processes that have a ripple effect necessary for life. Previously, protein complexes were viewed as static entities with biological...

2011-11-09 10:09:57

Just as a breeze causes leaves, branches and ultimately the tree to move, enzymes moving at the molecular level perform hundreds of chemical processes that have a ripple effect necessary for life. Protein complexes are often viewed as static entities with their biological functions understood in terms of direct interactions, but that isn't the case, as emphasized in a paper published November 8 in the online, open-access journal PLoS Biology. The work shows that the amount of flexibility in a...


Word of the Day
lambent
  • Licking.
  • Hence Running along or over a surface, as if in the act of licking; flowing over or along; lapping or bathing; softly bright; gleaming.
This word comes the Latin 'lambere,' to lick.
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