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Latest Enzymes Stories

2014-03-12 16:25:34

DALLAS, March 12, 2014 /PRNewswire/ -- The report "Specialty Enzymes Market by Source(Microorganism, Plant, Animal), Type(Carbohydrases, Protease, Lipase, Polymerases & Nucleases), Application(Pharmaceutical , Research & biotechnology, Diagnostic, Bio-Catalyst) & Geography - Global Trends & Forecasts to 2018", defines and segments the specialty enzymes market with an analysis and forecast of the global value for specialty enzymes. It also identifies the driving...

2014-02-20 08:31:52

- Milestone achieved for BI's initiation of Phase 1 study in beta-secretase (BACE) inhibitor program FORT WASHINGTON, Pa., Feb. 20, 2014 /PRNewswire/ -- Vitae Pharmaceuticals, Inc., a clinical-stage biopharmaceutical company focused on discovering and advancing novel, small molecule, best-in-class compounds, announced today that it has earned a $14 million milestone payment from Boehringer Ingelheim (BI) for BI's initiation of a Phase 1 clinical trial in the companies' beta-secretase...

Gordon Supercomputer Helps Guide New Drug Designs
2014-02-19 12:45:35

University of California, San Diego Single amyloid-beta monomers can pair up to form a variety of dimers that can aggregate into larger peptide rings that reside on cell membranes such as those pictured. This process has been implicated in the development of Alzheimer’s disease. This visualization shows the possible rings which have the most favorable energies of interactions with the membrane. The residues are colored white to represent apolar or hydrophobic areas, green for the polar...

Unraveling Mysteries Of Amyloid Beta Peptides To Detect And Treat Alzheimer's Disease
2014-02-18 07:41:38

American Institute of Physics Alzheimer's disease has long been marked by progress -- but not the kind of progress the medical community seeks. It is the most common form of dementia among older Americans, and its risk increases with increasing age; for those living with the disease, its ravages get worse over time; and as we move into the 21st century, it will place a greater and greater burden on society. The number of Americans living with Alzheimer's has doubled since 1980 and is...

2014-02-10 12:26:14

GOSSELIES, Belgium, February 10, 2014 /PRNewswire/ -- iTeos Therapeutics SA today announced the filing of the Company's first patent applications protecting proprietary inhibitors of the intracellular enzyme TDO2, which is expressed at high levels in specific cancers. iTeos Therapeutics has collaborated with Ludwig Cancer Research over the last year to identify small molecule inhibitors of the enzyme that display nanomolar potency, good selectivity, favorable pharmacokinetics...

2014-02-06 23:23:00

New research on carbonic anhydrase confirms its value as a treatment target, with limitations. Raleigh, NC (PRWEB) February 06, 2014 New research published in a European medical journal and reported by Surviving Mesothelioma suggests that a cell surface enzyme may provide a new target for mesothelioma therapy. Carbonic anhydrases are a large family of enzymes responsible for a range of biological processes. Carbonic anhydrase IX (CAIX) is a specific carbonic anhydrase involved in...

2014-01-13 10:21:10

New Study Pinpoints Structural Effects of V44M and V44A Mutations New research, led by Rensselaer Polytechnic Institute researcher Chunyu Wang, has solved one mystery in the development of Familial Alzheimer’s Disease (FAD), a genetic variant of the disease that affects a small fraction of the Alzheimer’s population. In a paper published January 6 in the journal Nature Communications, Wang and his team follow the trail of two genetic mutations – V44M and V44A – known to cause FAD,...

2014-01-07 23:02:06

Two new publications by a team from Western University of Health Sciences shed further light on the mechanisms of learning and memory, and neuronal degeneration. Pomona, California (PRWEB) January 07, 2014 Two new publications by a team from Western University of Health Sciences shed further light on the mechanisms of learning and memory, and neuronal degeneration. The first paper, “A molecular brake controls the magnitude of long-term potentiation,” by Yubin Wang, Guoqi Zhu, Victor...

2014-01-06 10:17:40

Earlier amyloid-beta assemblies may be one of the most important causes of Alzheimer's disease. Passive immunization of anti-amyloid-beta antibodies can reduce amyloid-beta burden and improved memory performance in various Alzheimer's disease animal models or patients. Screening humanized antibodies from a human Fab phage display library is an effective and quick method to obtain beta-amyloid oligomers. Thus, a recent study published in the Neural Regeneration Research (Vol. 8, No. 33, 2013)...

2013-12-16 12:00:42

Findings may be useful in design of future drugs and catalysts The theory of evolution suggests that present-day organisms evolved from earlier life forms. At the molecular level, evolution reshaped some of the enzymes that help complete chemical processes—such as converting food into energy—in humans and all other life forms. Now a University of Iowa researcher and his colleagues describe the evolution of various forms of the enzyme “dihydrofolate reductase” as it occurred...


Word of the Day
malpais
  • The ragged surface of a lava-flow.
'Malpais' translates from Spanish as 'bad land.'