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Latest Epidermal growth factor receptor Stories

2012-11-27 13:06:13

PKM2 slips into nucleus to promote cancer; potential biomarker and drug approach discovered Researchers at The University of Texas MD Anderson Cancer Center have tracked down a cancer-promoting protein's pathway into the cell nucleus and discovered how, once there, it fires up a glucose metabolism pathway on which brain tumors thrive. They also found a vital spot along the protein's journey that can be attacked with a type of drug not yet deployed against glioblastoma multiforme, the...

2012-09-05 21:19:07

A more-sensitive method to analyze protein interactions has uncovered a new way that cancer cells may use the cell-surface molecule HER3 to drive tumor progression following treatment with HER1 and HER2 inhibitors. The HER family of receptors has been linked to the development of a wide variety of human cancers. HER1 inhibitors such Iressa and HER2 inhibitors such as Herceptin are commonly used in the clinic for treatment of small cell lung carcinoma and breast cancer. A recent study...

2012-07-03 10:25:59

Drugs are first to topically deliver gene therapy via commercial moisturizers for skin disease treatment “Getting under your skin” takes on a brave new meaning thanks to Northwestern University research that could transform gene regulation. A team led by a physician-scientist and a chemist -- from the fields of dermatology and nanotechnology -- is the first to demonstrate the use of commercial moisturizers to deliver gene regulation technology that has great potential for...

2012-07-02 22:03:20

Discovery may lead to new, more powerful precision medicines that thwart resistance to the common lung cancer drug Tarceva People with lung cancer who are treated with the drug Tarceva face a daunting uncertainty: although their tumors may initially shrink, it's not a question of whether their cancer will return–it's a question of when. And for far too many, it happens far too soon. Now, a team of researchers at the University of California, San Francisco's Helen Diller Family...

2012-06-04 14:05:22

Census reveals unexpected variety of genes involved in cellular transport Scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, have conducted the first comprehensive census of human cells´ export workers. In a study published online today in Nature Cell Biology, they found an unexpected variety of genes involved in transporting molecules to the cell membrane and beyond. Using a combination of genetics and sophisticated microscopy, Rainer Pepperkok...

2012-06-04 04:24:11

(Ivanhoe Newswire) --Almost twelve million -- that´s how many cancer patients are living in the U.S. But what happens when the patients are no longer responsive to the drugs created to treat them? It´s a problem researchers at Case Western Reserve University are working to better understand. Researchers say overactive epidermal growth factor receptor (EGFR) signaling has been linked to the development of cancer. They found many patients have developed resistance to the drug...


Word of the Day
siliqua
  • A Roman unit of weight, 1⁄1728 of a pound.
  • A weight of four grains used in weighing gold and precious stones; a carat.
  • In anatomy, a formation suggesting a husk or pod.
  • The lowest unit in the Roman coinage, the twenty-fourth part of a solidus.
  • A coin of base silver of the Gothic and Lombard kings of Italy.
'Siliqua' comes from a Latin word meaning 'a pod.'
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