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Latest Epidermal growth factor receptor Stories

2012-06-04 04:24:11

(Ivanhoe Newswire) --Almost twelve million -- that´s how many cancer patients are living in the U.S. But what happens when the patients are no longer responsive to the drugs created to treat them? It´s a problem researchers at Case Western Reserve University are working to better understand. Researchers say overactive epidermal growth factor receptor (EGFR) signaling has been linked to the development of cancer. They found many patients have developed resistance to the drug...

2012-05-17 09:26:40

Targeted therapies have been studied for years, but recent laboratory research is providing robust clues about drugs that might work better in combination, particularly in treating cancers that have become resistant to therapy. That kind of information is behind a novel clinical trial at Georgetown Lombardi Comprehensive Cancer Center that combines cetuximab and lapatinib. Findings from this phase I study will be presented at the American Society of Clinical Oncology annual meeting in...

2012-03-21 13:48:50

Non-small cell lung cancer (NSCLC), the most common form of lung cancer, is usually treated with surgery and chemotherapy. However, a small group of patients can also be helped by treatment with tyrosine kinase inhibitors (TKI). New research published in BioMed Central's open access journal BMC Medicine, shows that blocking production of epidermal growth factor receptor (EGFR) using RNAi, alongside TKI (or antibody therapy), could enhance the effect of TKI on NSCLC cell death, and slow cell...

Image 1 - Scientists Learn How Insects 'Remodel' Their Bodies Between Life Stages
2012-03-01 04:47:52

Similar mechanisms may drive changes in puberty It´s one of life´s special moments: a child finds a fat caterpillar, puts it in a jar with a twig and a few leaves, and awakens one day to find the caterpillar has disappeared and an elegant but apparently lifeless case now hangs from the twig. Then, when the jar has been forgotten, soft beating against its glass walls calls attention to a new wonder: the jar now holds a fragile-winged butterfly or dusky moth with fringed...

2012-02-17 11:06:39

While there have been major advances in the detection, diagnosis, and treatment of tumors within the brain, brain cancer continues to have a very low survival rate in part to high levels of resistance to treatment. New research published in BioMed Central's open access journal Journal of Nanobiotechnology has used Sendai virus to transport Quantum Dots (Qdots) into brain cancer cells and to specifically bind Qdots to epidermal growth factor receptor (EGFR) which is often over-expressed and...

2012-02-07 09:55:31

Study may aid in development of improved therapies for glioblastoma A recent discovery by Van Andel Research Institute (VARI) scientists enables the prediction of patient sensitivity to proposed drug therapies for glioblastoma — the most common and most aggressive malignant brain tumor in humans. The study, published in January in the Proceedings of the National Academy of Science, investigated glioblastoma models characterized by cell signaling activation and gene amplification...

2012-02-06 22:28:20

Study may aid in development of improved therapies for glioblastoma A recent discovery by Van Andel Research Institute (VARI) scientists enables the prediction of patient sensitivity to proposed drug therapies for glioblastoma — the most common and most aggressive malignant brain tumor in humans. The study, published in January in the Proceedings of the National Academy of Science, investigated glioblastoma models characterized by cell signaling activation and gene amplification...


Word of the Day
jument
  • A beast of burden; also, a beast in general.
'Jument' ultimately comes from the Latin 'jugum,' yoke.
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