Latest Epithelial-mesenchymal transition Stories
By Ramis-Conde, Ignacio Drasdo, Dirk; Anderson, Alexander R A; Chaplain, Mark A J ABSTRACT In this article, we show, using a mathematical multiscale model, how cell adhesion may be regulated by interactions between E-cadherin and beta-catenin and how the control of cell adhesion may be related to cell migration, to the epithelial- mesenchymal transition and to invasion in populations of eukaryotic cells.
Researchers in the Life Sciences Division of Lawrence Berkeley National Laboratory have discovered a key molecular pathway by which MMP-3, an enzyme that normally helps remodel tissues, initiates the pathway to breast cancer. MMP-3 causes normal cells to express a protein, Rac1b, previously found only in cancers.
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