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Latest ERBB Stories

Researchers Discover New Route For Ovarian Cancer Spread
2014-07-15 03:14:42

University of Texas M. D. Anderson Cancer Center HER3-positive circulating tumor cells home in on omentum; new target to thwart metastasis Circulating tumor cells spread ovarian cancer through the bloodstream, homing in on a sheath of abdominal fatty tissue where it can grow and metastasize to other organs, scientists at The University of Texas MD Anderson Cancer Center report in Cancer Cell. "This completely new way of thinking about ovarian cancer metastasis provides new potential...

2013-08-07 10:44:28

New findings could lead to drugs that fight back when tumors don't respond to treatment Cancer drugs known as ErbB inhibitors have shown great success in treating many patients with lung, breast, colon and other types of cancer. However, ErbB drug resistance means that many other patients do not respond, and even among those who do, tumors commonly come back. A new study from MIT reveals that much of this resistance develops because a protein called AXL helps cancer cells to circumvent...

2012-03-06 06:22:01

(Ivanhoe Newswire)-- Metastasis is the spread of breast cancer due to an original tumor; this process is the leading cause of death for women with breast cancer, but now there´s hope. Researchers led by Stefan Offermanns and Thomas Worzfeld, in Germany produced data in mice and humans that implies that the protein Plexin-B1 represents a new potential therapeutic target to treat patients with breast cancer found to overexpress the molecule ErbB-2. AN Estimated 30% of all breast...

2012-03-02 01:33:11

The main cause of death in women with breast cancer is spread of the original tumor to distant sites, a process known as metastasis. New therapeutic targets are urgently needed. A team of researchers led by Stefan Offermanns and Thomas Worzfeld, at the Max-Planck-Institute for Heart and Lung Research, Germany, has now generated data in mice and humans that suggest that the protein Plexin-B1 represents a new candidate therapeutic target to treat patients with breast cancer found to overexpress...


Word of the Day
cock-a-hoop
  • Exultant; jubilant; triumphant; on the high horse.
  • Tipsy; slightly intoxicated.
This word may come from the phrase 'to set cock on hoop,' or 'to drink festively.' Its origin otherwise is unclear. A theory, according to the Word Detective, is that it's a 'transliteration of the French phrase 'coq a huppe,' meaning a rooster displaying its crest ('huppe') in a pose of proud defiance.' Therefore, 'cock-a-hoop' would 'liken a drunken man to a boastful and aggressive rooster.'
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