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Latest Erica Ollmann Saphire Stories

2011-11-21 10:29:15

Scientists from The Scripps Research Institute and the US Army's Medical Research Institute of Infectious Diseases have isolated and analyzed an antibody that neutralizes Sudan virus, a major species of ebolavirus and one of the most dangerous human pathogens. "We suspect that we've found a key spot for neutralizing ebolaviruses," said Scripps Research Associate Professor Erica Ollmann Saphire, who led the study with US Army virologist John M. Dye. The new findings, which were reported...

2011-11-15 09:39:50

Scientists at The Scripps Research Institute have determined the atomic structure of a protein that the Lassa fever virus uses to make copies of itself within infected cells. The structural data reveal an unexpected molecular crevice where the viral protein grips the viral genes, making this crevice a target for potential antiviral drugs. Lassa fever virus and other arenaviruses infect hundreds of thousands of people annually and are often deadly. Currently there is no specific therapy or...

2008-07-23 09:01:21

Scientists at the Scripps Research Institute have uncovered the structure of a critical protein from the Ebola Virus that allows viral entry in human cells. "This structure reveals how this critical piece of the virus is assembled and helps explain how the pathogen evades and exploits the human immune system," explained Erica Ollmann Saphire, the Scripps Research scientist who led the five-year effort. There is currently no cure for Ebola hemorrhagic fever. The virus is spread when...

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2008-07-10 15:40:52

Breakthrough findings point to targets for drugs and vaccines Described in the July 10, 2008 issue of the journal Nature, the research reveals the shape of the Ebola virus spike protein, which is necessary for viral entry into human cells, bound to an immune system antibody acting to neutralize the virus. The structure provides a major step forward in understanding how the deadly virus works, and may be useful in the development of potential Ebola virus vaccines, or treatments for those...


Word of the Day
mundungus
  • A stinking tobacco.
  • Offal; waste animal product; organic matter unfit for consumption.
This word comes from the Spanish 'mondongo,' tripe, entrails.