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Estrogen Receptor Expression Could Explain Why Males Are

Estrogen Receptor Expression Could Explain Why Males Are More Likely To Have Autism

Chuck Bednar for redOrbit.com - Your Universe Online The reason that girls are less likely than boys to suffer from autism may have something to do with the same sex hormone receptor responsible for helping protect them from stroke, according...

Latest Estrogen receptor Stories

2014-09-18 23:08:33

New Assay to Test Target Compounds for Anti-Obesity Therapeutics State College, PA (PRWEB) September 18, 2014 INDIGO Biosciences, a leading provider of nuclear receptor products and services announced today that it has released a new Human Estrogen-related Orphan Receptor Gamma (NR3B3; ERRγ) Assay System. Three different assay kits are available. ERRγ is naturally expressed in the central nervous system, and at lower relative levels in a variety of other tissue types, including kidney,...

2014-04-07 12:40:36

Obese male mice and normal weight female mice produce female pups that are overweight at birth and in childhood, and have increased number of "terminal end buds" in their breast tissue — the site where cancer often develops in rodents. The findings, presented by a Georgetown Lombardi Comprehensive Cancer Center researcher at the AACR Annual Meeting 2014, come from one of the first animal studies to examine the impact of paternal obesity on future generations' cancer risk. In addition,...

Smoking Bad Not Only For Lungs, But Also For Breasts: Study
2014-02-10 13:19:11

[ Watch the Video: Smoking Can Also Give You Breast Cancer ] Brett Smith for redOrbit.com - Your Universe Online Cigarette smoking has frequently been linked to cancers of the respiratory system, but a new study has found that smoking can also greatly increase the risk of a certain breast cancer in women. According to a study recently published in the journal Cancer, young women who smoke a pack per day for a decade or longer have a much greater risk of having the most common kind of...

Genetic Markers May Signify Response To Breast Cancer Therapy
2013-06-13 19:09:12

Brett Smith for redOrbit.com — Your Universe Online New research from the Mayo Clinic has identified favorable genetic variations that increase the chances of a positive response to preventive breast cancer therapy with the drugs tamoxifen and raloxifene, according to a new report in the journal Cancer Discovery. "Our findings are important because we identified genetic factors that could eventually be used to select women who should be offered the drugs for prevention,"...

2013-04-23 18:47:52

Tamoxifen is a time-honored breast cancer drug used to treat millions of women with early-stage and less-aggressive disease, and now a University of Rochester Medical Center team has shown how to exploit tamoxifen´s secondary activities so that it might work on more aggressive breast cancer. The research, published in the journal EMBO Molecular Medicine, is a promising development for women with basal-like breast cancer, sometimes known as triple-negative disease. This subtype has a...

2013-03-13 17:47:27

On the football field, the neophyte fan focuses on the receiver, whose daring catch and dash for the goal line captures the attention. However, focusing on that one player means the fan misses the contributions of the quarterback, the blockers and the other players who make that run happen. The same is true in the cell, where too often a single finding about one protein, enzyme or receptor seems to solve a problem. In an online report in the journal Nucleic Acids Research, Dr. Michael...

Milk Protein Found In Breast Cells Triggers Aggressive Cancer
2012-12-28 12:38:27

Lawrence LeBlond for redOrbit.com - Your Universe Online Health advocates for years have told us that milk does the body good. Health experts have also been keen on promoting the positive effects breastfed milk has on childhood development. But now, milk is getting a bad rap--particularly, a certain protein found in breast milk is the problem. Scientists have recently discovered that this protein, called ELF5, which is found in all breast cells and is responsible for milk production, is...

Negative BPA Effects Begin When Metabolized
2012-10-05 14:49:53

Alan McStravick for redOrbit.com - Your Universe Online Roughly 9 out of 10 Americans are walking around with a highly toxic synthetic chemical surging through their systems. Bisphenol A (BPA) is a petroleum-based chemical that is widely used in the production of plastic products such as bottles, food can linings and water supply lines. And as these plastics degrade over time, humans ingest more and more BPA. Less than 3 months ago, the FDA acted upon evidence found in several studies...

2012-07-02 23:11:52

Preclinical imaging of progesterone receptor signals usefulness of biomarker in determining effectiveness of therapy Research published in the July issue of The Journal of Nuclear Medicine shows imaging progesterone receptor (PR) status also may be able to identify responders and nonresponders to endocrine therapy at an early stage. Estrogen receptor-α(ERα) status is an important factor in determining the most appropriate treatment for breast cancer patients,...

2012-07-02 21:42:17

Researchers at Georgetown Lombardi Comprehensive Cancer Center have uncovered a single molecule they say is a major determinant of resistance to anti-estrogen therapy used to treat or prevent breast cancer in high-risk women. In the July 1 issue of Cancer Research, the scientists say glucose-regulated protein 78 (GRP78), activated as breast cells undergo stress induced by the agents tamoxifen and fulvestrant, turns off apoptosis, a cell death response, and turns on autophagy. In autophagy,...


Word of the Day
grass-comber
  • A landsman who is making his first voyage at sea; a novice who enters naval service from rural life.
According to the OED, a grass-comber is also 'a sailor's term for one who has been a farm-labourer.'